4-mercapto-nicotinic acid-(2,4-dichloro-benzylidenehydrazide)

Base Information

• Chemical Name: 4-mercapto-nicotinic acid-(2,4-dichloro-benzylidenehydrazide)
• CAS No.: 99514-01-9
• Molecular Formula: C₁₃H₉Cl₂N₃OS
• Molecular Weight: 326.206
• Mol file: 99514-01-9.mol

Synonyms:

Chemical Property of 4-mercapto-nicotinic acid-(2,4-dichloro-benzylidenehydrazide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-mercapto-nicotinic acid-(2,4-dichloro-benzylidenehydrazide)

There total 5 articles about 4-mercapto-nicotinic acid-(2,4-dichloro-benzylidenehydrazide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-mercaptopyridine-3-carboxylic acid methyl ester (74470-38-5) → 4-mercapto-nicotinic acid-(2,4-dichloro-benzylidenehydrazide) (99514-01-9)

Guidance literature:

Multi-step reaction with 2 steps

1: N₂H₄+H₂O

2: acetic acid; methanol

With methanol; hydrazine hydrate; acetic acid;

DOI:10.1021/jo01370a002

Reference yield:

[1,2]dithiolo[4,3-c]pyridine-3-thione (65282-64-6) → 4-mercapto-nicotinic acid-(2,4-dichloro-benzylidenehydrazide) (99514-01-9)

Guidance literature:

Multi-step reaction with 4 steps

1: aqueous NaOH

2: HCl

3: N₂H₄+H₂O

4: acetic acid; methanol

With hydrogenchloride; methanol; sodium hydroxide; hydrazine hydrate; acetic acid;

DOI:10.1021/jo01370a002

Reference yield:

4-mercaptopyridine-3-carboxylic acid (18103-73-6) → 4-mercapto-nicotinic acid-(2,4-dichloro-benzylidenehydrazide) (99514-01-9)

Guidance literature:

Multi-step reaction with 3 steps

1: HCl

2: N₂H₄+H₂O

3: acetic acid; methanol

With hydrogenchloride; methanol; hydrazine hydrate; acetic acid;

DOI:10.1021/jo01370a002

upstream raw materials:

2,4-dichlorobenzaldeyhde

4-mercaptopyridine-3-carboxylic acid methyl ester

4-hydroxynicotinic acid

4-mercaptopyridine-3-carboxylic acid