Technology Process of (+/-)-O-benzylisobharatamine
There total 9 articles about (+/-)-O-benzylisobharatamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 84 percent / triethylamine / benzene / 3.5 h / Heating
2: 2.) POCl3, 3.) NABH4 / 1.) benzene, irradiation, 2 h, 2.) 60-80 deg C, 2.5 h, 3.) MeOH, 0 deg C, 0.5 h, then room temperature
With
sodium tetrahydroborate; triethylamine; trichlorophosphate;
In
benzene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 84 percent / triethylamine / benzene / 3.5 h / Heating
2: 2.) POCl3, 3.) NABH4 / 1.) benzene, irradiation, 2 h, 2.) 60-80 deg C, 2.5 h, 3.) MeOH, 0 deg C, 0.5 h, then room temperature
With
sodium tetrahydroborate; triethylamine; trichlorophosphate;
In
benzene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1) n-butyllithium / 1) ether, room temperature, 20 h, 2) room temperature, 2 h
2: ethyl chloroformate, sodium bicarbonate / benzene / 1 h
3: dimethylformamide / 6 h / Ambient temperature
4: potassium hydroxide / methanol; H2O / 2 h / Ambient temperature
5: 86 percent / ethanol / 24 h / Ambient temperature
6: 1) PCl5, 2) sodium borohydride / 1) chloroform, room temperature, 2) methanol, room temperature, 1 h
With
potassium hydroxide; sodium tetrahydroborate; n-butyllithium; phosphorus pentachloride; chloroformic acid ethyl ester; sodium hydrogencarbonate;
In
methanol; ethanol; water; N,N-dimethyl-formamide; benzene;