2-Cyano-2-(1-phenyl-ethyl)-succinic acid dimethyl ester

Base Information

• Chemical Name: 2-Cyano-2-(1-phenyl-ethyl)-succinic acid dimethyl ester
• CAS No.: 84454-41-1
• Molecular Formula: C₁₅H₁₇NO₄
• Molecular Weight: 275.304
• Mol file: 84454-41-1.mol

Synonyms:

Chemical Property of 2-Cyano-2-(1-phenyl-ethyl)-succinic acid dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-Cyano-2-(1-phenyl-ethyl)-succinic acid dimethyl ester

There total 1 articles about 2-Cyano-2-(1-phenyl-ethyl)-succinic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Dimethyl 1-cyanoethane-1,2-dicarboxylate (6283-71-2) → 2-Cyano-2-(1-phenyl-ethyl)-succinic acid dimethyl ester (84454-41-1)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; Ambient temperature;

DOI:10.1021/jo00153a032

Reference yield:

2-Cyano-2-(1-phenyl-ethyl)-succinic acid dimethyl ester (84454-41-1) → 2-(1-Cyano-2-phenyl-propyl)-malonic acid dimethyl ester (89991-56-0)

Guidance literature:

With potassium hydride; In 1,2-dimethoxyethane; room temperature, 3 h or reflux, 0.5 h;

DOI:10.1021/jo00153a032

upstream raw materials:

Dimethyl 1-cyanoethane-1,2-dicarboxylate

Downstream raw materials:

2-(1-Cyano-2-phenyl-propyl)-malonic acid dimethyl ester

Refernces