2-(2-Bromo-4,6-dichlorophenoxy)acetic acid

Base Information

• Chemical Name: 2-(2-Bromo-4,6-dichlorophenoxy)acetic acid
• CAS No.: 103951-16-2
• Molecular Formula: C8H5BrCl2O3
• Molecular Weight: 299.93400
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID10544102
• Wikidata: Q82421093
• Mol file: 103951-16-2.mol

Synonyms:2-(2-BROMO-4,6-DICHLOROPHENOXY)ACETIC ACID;103951-16-2;(2-bromo-4,6-dichlorophenoxy)acetic acid;2-(2-BROMO-4,6-DICHLOROPHENOXY)ACETICACID;DTXSID10544102;AKOS000319566;6-bromo-2,4-dichlorophenoxyacetic acid;AE-848/36231017

Chemical Property of 2-(2-Bromo-4,6-dichlorophenoxy)acetic acid

Chemical Property:

• PSA: 46.53000
• LogP: 3.21930
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 297.87991
• Heavy Atom Count: 14
• Complexity: 215

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-Bromo-4,6-dichlorophenoxy)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1Cl)OCC(=O)O)Br)Cl

Technology Process of 2-(2-Bromo-4,6-dichlorophenoxy)acetic acid

There total 2 articles about 2-(2-Bromo-4,6-dichlorophenoxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl bromoacetate (105-36-2) → (2-bromo-4,6-dichloro-phenoxy)-acetic acid (103951-16-2)

Guidance literature:

With ethanol; anschliessend Erwaermen mit wss. Natronlauge;

Reference yield:

2-bromo-4,6-dichlorophenol (4524-77-0) + chloroacetic acid (79-11-8) → (2-bromo-4,6-dichloro-phenoxy)-acetic acid (103951-16-2)

Guidance literature:

With sodium hydroxide; for 4h; Heating; pH 10 - 12;

Reference yield: 50.0%

(2-bromo-4,6-dichloro-phenoxy)-acetic acid (103951-16-2) → C8H5(3)HCl2O3 (103951-18-4)

Guidance literature:

With calcium carbonate; trimethyleneglycol; In 1,4-dioxane;

upstream raw materials:

2-bromo-4,6-dichlorophenol

chloroacetic acid

ethyl bromoacetate

Downstream raw materials:

C₈H₅⁽³⁾HCl₂O₃

Refernces