beta-Ethoxyphenethyl alcohol

Base Information

• Chemical Name: beta-Ethoxyphenethyl alcohol
• CAS No.: 36747-96-3
• Molecular Formula: C10H14 O2
• Molecular Weight: 166.22
• Hs Code.: 2909499000
• European Community (EC) Number: 253-184-1
• DSSTox Substance ID: DTXSID00957964
• Mol file: 36747-96-3.mol

Synonyms:beta-Ethoxyphenethyl alcohol;36747-96-3;EINECS 253-184-1;1-Ethoxy-2-phenylethan-1-ol;SCHEMBL1356948;DTXSID00957964

Chemical Property of beta-Ethoxyphenethyl alcohol

Chemical Property:

• Boiling Point: 257.5°Cat760mmHg
• Flash Point: 103.8°C
• PSA: 29.46000
• Density: 1.039g/cm³
• LogP: 1.75650
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 166.099379685
• Heavy Atom Count: 12
• Complexity: 108

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(CC1=CC=CC=C1)O

Technology Process of beta-Ethoxyphenethyl alcohol

There total 15 articles about beta-Ethoxyphenethyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

styrene oxide (96-09-3) + ethanol (64-17-5) → 2-ethoxy-2-phenylethanol (36747-96-3)

Guidance literature:

With erbium(III) triflate; at 25 ℃; for 0.75h;

DOI:10.1055/s-0029-1216956

Reference yield: 81.0%

methyl α-ethoxy-α-phenylacetate (65792-30-5) → 2-ethoxy-2-phenylethanol (36747-96-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; Heating;

DOI:10.1002/1099-0690(200011)2000:21<3527::aid-ejoc3527>3.3.co;2-g

Reference yield: 72.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + ethanol (64-17-5) → styrene oxide (96-09-3) + 2-ethoxy-2-phenylethanol (36747-96-3)

Guidance literature:

With methyltrioxorhenium(VII)/(1S,2S)-1,2-diaminocyclohexane adduct; urea hydrogen peroxide adduct; at 20 ℃; for 24h;

DOI:10.1016/j.jcat.2008.05.004

upstream raw materials:

styrene oxide

ethanol

ethyl α-ethoxy-α-phenylacetate

methyl α-ethoxy-α-phenylacetate

Downstream raw materials:

Benzoic acid 2-ethoxy-2-phenyl-ethyl ester

phenyl (2-phenyl-2-ethoxy ethyl)sulphone

phenyl (β-ethoxy-β-phenylethyl)sulphide

2-ethoxy-2-phenylethyl methanesulfonate

Refernces

• 1、 Tan, Yan-Xi,Yang, Xue,Li, Bei-Bei,Yuan, Daqiang. "Rational design of a flu -type heterometallic cluster-based Zr-MOF". . p. 13671 - 13674. Retrieved 2016.
• 2、 Chaudhary, Pooja,Deepa,Meena, Dhan Raj,Aalam, Mohd Jubair,Yadav, Geeta Devi,Singh, Surendra. "Cellulose sulfate: An efficient heterogeneous catalyst for the ring-opening of epoxides with alcohols and anilines". supporting information. p. 1834 - 1846. Retrieved 2021/05/10.
• 3、 Nicholls, Leo D. M.,Wennemers, Helma. "Synergistic Peptide and Gold Catalysis: Enantioselective Addition of Branched Aldehydes to Allenamides". supporting information. p. 17559 - 17564. Retrieved 2021/10/19.