ethyl (S)-N-Boc-2-amino-5-hydroxypentanoate

Base Information

• Chemical Name: ethyl (S)-N-Boc-2-amino-5-hydroxypentanoate
• CAS No.: 471282-35-6
• Molecular Formula: C₁₂H₂₃NO₅
• Molecular Weight: 261.318
• Mol file: 471282-35-6.mol

Synonyms:

Chemical Property of ethyl (S)-N-Boc-2-amino-5-hydroxypentanoate

Chemical Property:

Purity/Quality:

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Useful:

Technology Process of ethyl (S)-N-Boc-2-amino-5-hydroxypentanoate

There total 1 articles about ethyl (S)-N-Boc-2-amino-5-hydroxypentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

(S)-ethyl N-tert-butoxycarbonylpyroglutamate (144978-35-8,144978-12-1,251924-83-1) → ethyl (S)-N-Boc-2-amino-5-hydroxypentanoate (471282-35-6) + [(1S)-4-hydroxy-1-(hydroxymethyl)butyl]carbamic acid tert-butyl ester (162955-48-8,397246-12-7)

Guidance literature:

With Cp*RuCl{(C6H5)2P-(CH2)2NH2-κ2-P,N}; potassium tert-butylate; hydrogen; In tert-butyl alcohol; at 80 ℃; for 24h; under 22502.3 Torr; Autoclave;

DOI:10.1002/anie.200805307

upstream raw materials:

(S)-ethyl N-tert-butoxycarbonylpyroglutamate

Refernces