[pentane-5,5,5-⁽³⁾H₃]-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylresorcinol

Base Information

• Chemical Name: [pentane-5,5,5-⁽³⁾H₃]-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylresorcinol
• CAS No.: 1305300-58-6
• Molecular Formula: C₂₁H₃₀O₂
• Molecular Weight: 320.444
• Mol file: 1305300-58-6.mol

Synonyms:

Chemical Property of [pentane-5,5,5-⁽³⁾H₃]-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylresorcinol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [pentane-5,5,5-⁽³⁾H₃]-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylresorcinol

There total 9 articles about [pentane-5,5,5-⁽³⁾H₃]-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylresorcinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C33H55(3)H3O2Si2 (1305300-57-5) → [pentane-5,5,5-(3)H3]-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylresorcinol (1305300-58-6)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/jlcr.1840

Reference yield:

C20H31BO2 → [pentane-5,5,5-(3)H3]-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylresorcinol (1305300-58-6)

Guidance literature:

Multi-step reaction with 7 steps

1: dihydrogen peroxide; sodium hydroxide / water; toluene

2: carbon tetrabromide; triphenylphosphine / acetonitrile / 1 h / 20 °C / Cooling with ice

3: boron tribromide / dichloromethane; 1,2-dichloro-ethane / 1.5 h / Reflux

4: boron trifluoride diethyl etherate; magnesium sulfate / dichloromethane / 1 h / -40 °C / Inert atmosphere

5: 2,6-dimethylpyridine / dichloromethane / 20 °C

6: dilithium tetrachlorocuprate / tetrahydrofuran; diethyl ether / 4 h / 20 °C

7: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere

With 2,6-dimethylpyridine; dilithium tetrachlorocuprate; carbon tetrabromide; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; dihydrogen peroxide; boron tribromide; magnesium sulfate; triphenylphosphine; sodium hydroxide; In tetrahydrofuran; diethyl ether; dichloromethane; water; 1,2-dichloro-ethane; toluene; acetonitrile;

DOI:10.1002/jlcr.1840

Reference yield:

4-(3,5-dihydroxyphenyl)-1-bromobutane (1260669-57-5) → [pentane-5,5,5-(3)H3]-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)-3-pentylresorcinol (1305300-58-6)

Guidance literature:

Multi-step reaction with 4 steps

1: boron trifluoride diethyl etherate; magnesium sulfate / dichloromethane / 1 h / -40 °C / Inert atmosphere

2: 2,6-dimethylpyridine / dichloromethane / 20 °C

3: dilithium tetrachlorocuprate / tetrahydrofuran; diethyl ether / 4 h / 20 °C

4: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere

With 2,6-dimethylpyridine; dilithium tetrachlorocuprate; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; magnesium sulfate; In tetrahydrofuran; diethyl ether; dichloromethane;

DOI:10.1002/jlcr.1840

upstream raw materials:

4-(3,5-dihydroxyphenyl)-1-bromobutane

5-(4-bromobutyl)-4-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-1,3-benzenediol

5-(4-bromobutyl)-3,5-bis(tert-butyldimethylsilyloxy)-2-(6-isopropenyl-3-methyl-2-cyclohexenyl)benzene

C₃₃H₅₅⁽³⁾H₃O₂Si₂

Refernces