C₂₆H₂₉N₂O₂⁽¹⁺⁾*I^(1-)

Base Information

• Chemical Name: C₂₆H₂₉N₂O₂⁽¹⁺⁾*I^(1-)
• CAS No.: 1352626-59-5
• Molecular Formula: C₂₆H₂₉N₂O₂*I
• Molecular Weight: 528.433
• Mol file: 1352626-59-5.mol

Synonyms:

Chemical Property of C₂₆H₂₉N₂O₂⁽¹⁺⁾*I^(1-)

Chemical Property:

Purity/Quality:

2-{2-[7-(Diethylamino)-2-oxo-2H-1-benzopyran-3-yl]ethenyl}-1,3,3-trimethyl-3H-indolium iodide for fluorescence ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 22103985
• Hazard Codes: 22103985

MSDS Files:

Useful:

Technology Process of C₂₆H₂₉N₂O₂⁽¹⁺⁾*I^(1-)

There total 7 articles about C₂₆H₂₉N₂O₂⁽¹⁺⁾*I^(1-) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.3%

1,3,3-trimethyl-3H-indol-1-ium iodide + 7-diethylaminocoumarine-3-aldehyde (57597-64-5) → C26H29N2O2(1+)*I(1-) (1352626-59-5)

Guidance literature:

With sodium acetate; In ethanol; at 85 ℃; for 16h;

Reference yield: 73.0%

1,2,3,3-tetramethyl-3H-indolium iodide (5418-63-3) + 7-diethylaminocoumarine-3-aldehyde (57597-64-5) → C26H29N2O2(1+)*I(1-) (1352626-59-5)

Guidance literature:

In ethanol; for 12h; Reflux;

DOI:10.1039/c1cc15721c

Reference yield:

4-(Diethylamino)salicylaldehyde (17754-90-4) → C26H29N2O2(1+)*I(1-) (1352626-59-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: piperidine / ethanol / 6 h / Reflux

1.2: 6 h

1.3: 0.5 h / pH Ca_.5

2.1: trichlorophosphate / 0.5 h / 50 °C / Inert atmosphere

2.2: 12 h / 60 °C

3.1: ethanol / 5 h / Reflux; Inert atmosphere

With piperidine; trichlorophosphate; In ethanol;

DOI:10.1039/c9nj03846a

upstream raw materials:

1,2,3,3-tetramethyl-3H-indolium iodide

7-diethylaminocoumarine-3-aldehyde

4-(Diethylamino)salicylaldehyde

7-diethylamino-2H-benzopyran-2-one

Refernces

• 1、 Lv, Xin,Liu, Jing,Liu, Yunlong,Zhao, Yun,Sun, Yuan-Qiang,Wang, Pi,Guo, Wei. "Ratiometric fluorescence detection of cyanide based on a hybrid coumarin-hemicyanine dye: The large emission shift and the high selectivity". . p. 12843 - 12845. Retrieved 2011.
• 2、 Tirla, Alina,Rivera-Fuentes, Pablo. "Induction of intracellular reductive stress with a photoactivatable phosphine probe". . p. 241 - 244. Retrieved 2018.
• 3、 Fang, Hongbao,Chen, Yuncong,Shi, Xiangchao,Bai, Yang,Chen, Zhongyan,Han, Zhong,Zhang, Yuming,He, Weijiang,Guo, Zijian. "Tuning lipophilicity for optimizing the H2S sensing performance of coumarin-merocyanine derivatives". . p. 14800 - 14805. Retrieved 2019.
• 4、 -. "Application of merocyanine-coumarin fluorophore to detection of hydrogen sulfide in mitochondria". Paragraph 0026; 0030-0032. . Retrieved 2020/02/27.