Acetic acid, (nitrooxy)-, 1,3-dimethyl-3-phenylbutyl ester

Base Information

• Chemical Name: Acetic acid, (nitrooxy)-, 1,3-dimethyl-3-phenylbutyl ester
• CAS No.: 104198-10-9
• Molecular Formula: C14H19NO5
• Molecular Weight: 281.309
• Mol file: 104198-10-9.mol

Synonyms:

Chemical Property of Acetic acid, (nitrooxy)-, 1,3-dimethyl-3-phenylbutyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetic acid, (nitrooxy)-, 1,3-dimethyl-3-phenylbutyl ester

There total 2 articles about Acetic acid, (nitrooxy)-, 1,3-dimethyl-3-phenylbutyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Bromo-acetic acid 1,3-dimethyl-3-phenyl-butyl ester (104198-02-9) → Nitrooxy-acetic acid 1,3-dimethyl-3-phenyl-butyl ester (104198-10-9)

Guidance literature:

With silver nitrate; In acetonitrile; for 48h; Ambient temperature;

DOI:10.1021/jo00375a006

Reference yield:

4-methyl-4-phenyl-pentan-2-ol (2035-93-0) → Nitrooxy-acetic acid 1,3-dimethyl-3-phenyl-butyl ester (104198-10-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / p-toluenesulfonic acid monohydrate / benzene / 24 h / Heating

2: 85 percent / AgNO₃ / acetonitrile / 48 h / Ambient temperature

With toluene-4-sulfonic acid; silver nitrate; In acetonitrile; benzene;

DOI:10.1021/jo00375a006

Reference yield: 91.0%

Nitrooxy-acetic acid 1,3-dimethyl-3-phenyl-butyl ester (104198-10-9) → Oxo-acetic acid 1,3-dimethyl-3-phenyl-butyl ester (99457-86-0)

Guidance literature:

With sodium acetate; In dimethyl sulfoxide; for 1h; Ambient temperature;

DOI:10.1021/jo00375a006

upstream raw materials:

Bromo-acetic acid 1,3-dimethyl-3-phenyl-butyl ester

4-methyl-4-phenyl-pentan-2-ol

Downstream raw materials:

Oxo-acetic acid 1,3-dimethyl-3-phenyl-butyl ester

Refernces