Technology Process of 1,4,7,10,13,16-Hexaoxacyclononadecane,
18-[[[[2-[(1,4,7,10,13,16-hexaoxacyclononadec-18-ylmethyl)dithio]phen
yl]methyl]thio]methyl]-
There total 6 articles about 1,4,7,10,13,16-Hexaoxacyclononadecane,
18-[[[[2-[(1,4,7,10,13,16-hexaoxacyclononadec-18-ylmethyl)dithio]phen
yl]methyl]thio]methyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
n-butyllithium;
In
tetrahydrofuran; hexane;
for 0.5h;
Ambient temperature;
DOI:10.1021/ja00282a033
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 90 percent / triethylamine / tetrahydrofuran / 2.5 h / Ambient temperature
2: 93 percent / lithium aluminum hydride / diethyl ether / 8 h / Ambient temperature
3: 91 percent / triethylamine / CH2Cl2 / 0.17 h / -10 °C
4: tetrahydrofuran / 0.5 h / Ambient temperature
5: 1.) silver nitrate; 2.) hydrogen sulfide / 1.) water, methanol, heating, 10 min; 2.) methylene chloride, 5 min
6: 94 percent / 1.) n-butyllithium / hexane; tetrahydrofuran / 0.5 h / Ambient temperature
With
lithium aluminium tetrahydride; n-butyllithium; hydrogen sulfide; silver nitrate; triethylamine;
In
tetrahydrofuran; diethyl ether; hexane; dichloromethane;
DOI:10.1021/ja00282a033
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 91 percent / triethylamine / CH2Cl2 / 0.17 h / -10 °C
2: tetrahydrofuran / 0.5 h / Ambient temperature
3: 1.) silver nitrate; 2.) hydrogen sulfide / 1.) water, methanol, heating, 10 min; 2.) methylene chloride, 5 min
4: 94 percent / 1.) n-butyllithium / hexane; tetrahydrofuran / 0.5 h / Ambient temperature
With
n-butyllithium; hydrogen sulfide; silver nitrate; triethylamine;
In
tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ja00282a033