Technology Process of C13H17ClN2O
There total 6 articles about C13H17ClN2O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C19H19ClN2O3; methyl iodide;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
With
trifluoroacetic acid;
at 50 ℃;
DOI:10.1016/j.bmcl.2011.02.009
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium tetrahydroborate; cobalt(II) chloride / methanol / 0.33 h / 100 °C / Microwave irradiation
2.1: sodium hydrogencarbonate / tetrahydrofuran / 20 °C
3.1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C
3.2: 50 °C
With
sodium tetrahydroborate; sodium hydride; sodium hydrogencarbonate; cobalt(II) chloride;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.02.009
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: thionyl chloride / 20 °C
2.1: sodium methylate / methanol / 20 °C
3.1: potassium tert-butylate / tert-butyl alcohol / 20 °C
4.1: hydrogenchloride / diethyl ether; water / 4 h / 20 °C
5.1: sodium tetrahydroborate; cobalt(II) chloride / methanol / 0.33 h / 100 °C / Microwave irradiation
6.1: sodium hydrogencarbonate / tetrahydrofuran / 20 °C
7.1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C
7.2: 50 °C
With
hydrogenchloride; sodium tetrahydroborate; thionyl chloride; potassium tert-butylate; sodium methylate; sodium hydride; sodium hydrogencarbonate; cobalt(II) chloride;
In
tetrahydrofuran; methanol; diethyl ether; water; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1016/j.bmcl.2011.02.009