PYRROLIDINMETHYLCARBAMATE

Base Information

• Chemical Name: PYRROLIDINMETHYLCARBAMATE
• CAS No.: 56475-80-0
• Molecular Formula: C6H11 N O2
• Molecular Weight: 129.159
• Mol file: 56475-80-0.mol

Synonyms:1-Carbomethoxypyrrolidine;1-Methoxycarbonylpyrrolidine; Methyl 1-pyrrolidinecarboxylate;N-Carbomethoxypyrrolidine; N-Methoxycarbonylpyrrolidine; NSC 30495

Chemical Property of PYRROLIDINMETHYLCARBAMATE

Chemical Property:

• Vapor Pressure: 1.21mmHg at 25°C
• Boiling Point: 174.4°C at 760 mmHg
• Flash Point: 59.3°C
• PSA: 29.54000
• Density: 1.1g/cm³
• LogP: 0.78650

Purity/Quality:

97% ^*data from raw suppliers

1-Methoxycarbonyl-pyrrolidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of PYRROLIDINMETHYLCARBAMATE

There total 2 articles about PYRROLIDINMETHYLCARBAMATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

pyrrolidine (123-75-1) + 2-t,3-t-diisopropyltriaziridin-1-r-carbonsaure-methylester → N-(methoxycarbonyl)pyrrolidine (56475-80-0) + (1E)-1,3-diisopropyltriazen (84713-95-1,118644-04-5) + (2E)-2,3-Diisopropyl-azimin-1-carbonsaeure-methylester (82317-28-0,82317-30-4)

Guidance literature:

In chloroform-d1; at 60 ℃; Product distribution; thermolysis;

DOI:10.1002/hlca.19880710132

Reference yield: 69.0%

N-benzylpyrrolidine (29897-82-3) + methyl chloroformate (79-22-1) → methyl N-benzyl-(3-chlorobutyl)-carbamate + N-(methoxycarbonyl)pyrrolidine (56475-80-0)

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.1021/ol062128c

Reference yield: 100.0%

N-(methoxycarbonyl)pyrrolidine (56475-80-0) → pyrrolidine (123-75-1)

Guidance literature:

With tert-butylamine; In methanol; for 3h; Heating;

DOI:10.1016/j.tetlet.2006.11.024

upstream raw materials:

pyrrolidine

N-benzylpyrrolidine

methyl chloroformate

Downstream raw materials:

methyl 2-methoxypyrrolidine-1-carboxylate

pyrrolidine

1-pyrrolidinecarbonyl chloride

methyl 2-hydroxy-1-pyrrolidinecarboxylate

Refernces

• 1、 Hipert, Hans,Dreiding, Andre S.. "Triaziridines. Ring Openings of Triaziridines". . p. 277 - 291. Retrieved 2007/10/02.