Decanamide, N-(2-aminoethyl)-

Base Information

• Chemical Name: Decanamide, N-(2-aminoethyl)-
• CAS No.: 104538-36-5
• Molecular Formula: C12H26N2O
• Molecular Weight: 214.351
• DSSTox Substance ID: DTXSID20480421
• Nikkaji Number: J1.463.762A
• Wikidata: Q82315176
• Mol file: 104538-36-5.mol

Synonyms:Decanamide, N-(2-aminoethyl)-;104538-36-5;SCHEMBL1984951;DTXSID20480421;AKOS014787395

Chemical Property of Decanamide, N-(2-aminoethyl)-

Chemical Property:

• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 10
• Exact Mass: 214.204513457
• Heavy Atom Count: 15
• Complexity: 149

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCC(=O)NCCN

Technology Process of Decanamide, N-(2-aminoethyl)-

There total 1 articles about Decanamide, N-(2-aminoethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

ethylenediamine (107-15-3,85404-18-8) + N-benzyl-N-methyldecanoic acid amide (152328-82-0) → N-methyldecanoic acid amide (23220-25-9) + N-(2-aminoethyl)decanoic acid amide (104538-36-5)

Guidance literature:

With lithium; tert-butylamine; at -18 - 20 ℃; for 7h;

DOI:10.1021/jo0008136

Reference yield: 86.0%

N-(2-aminoethyl)decanoic acid amide (104538-36-5) + 3-(benzyloxycarbonylamino)propanoic acid (2304-94-1) → benzyl (3-((2-decanamidoethyl)amino)-3-oxopropyl)carbamate

Guidance literature:

N-(2-aminoethyl)decanoic acid amide; 3-(benzyloxycarbonylamino)propanoic acid; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

With HATU; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/c7cc02427d

Reference yield: 86.0%

N-(2-aminoethyl)decanoic acid amide (104538-36-5) + N-Cbz-Ala (1142-20-7) → benzyl (S)-(1-((2-decananamidoethyl)amino)-1-oxopropan-2-yl)carbamate

Guidance literature:

N-(2-aminoethyl)decanoic acid amide; N-Cbz-Ala; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

With HATU; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/c7cc02427d

upstream raw materials:

ethylenediamine

N-benzyl-N-methyldecanoic acid amide

Refernces