1,7,7-trimethyl-6-endo-phenylbicyclo<2.2.1>hept-2-yl-exo-methoxypropionamide

Base Information

• Chemical Name: 1,7,7-trimethyl-6-endo-phenylbicyclo<2.2.1>hept-2-yl-exo-methoxypropionamide
• CAS No.: 128321-79-9
• Molecular Formula: C₂₀H₂₉NO₂
• Molecular Weight: 315.456
• Mol file: 128321-79-9.mol

Synonyms:

Chemical Property of 1,7,7-trimethyl-6-endo-phenylbicyclo<2.2.1>hept-2-yl-exo-methoxypropionamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,7,7-trimethyl-6-endo-phenylbicyclo<2.2.1>hept-2-yl-exo-methoxypropionamide

There total 2 articles about 1,7,7-trimethyl-6-endo-phenylbicyclo<2.2.1>hept-2-yl-exo-methoxypropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

3-Methoxypropionitrile (110-67-8) + 5,5,6-trimethyl-2-phenylbicyclo<2.2.1>heptan-2-endo-ol (128355-16-8) → 1,7,7-trimethyl-6-endo-phenylbicyclo<2.2.1>hept-2-yl-exo-methoxypropionamide (128321-79-9)

Guidance literature:

With sulfuric acid; for 10h; Ambient temperature;

Reference yield:

5,5,6-trimethylbicyclo[2.2.1]heptan-2-one (3292-05-5) → 1,7,7-trimethyl-6-endo-phenylbicyclo<2.2.1>hept-2-yl-exo-methoxypropionamide (128321-79-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / diethyl ether / 4 h / Ambient temperature

2: 37 percent / conc. H₂SO₄ / 10 h / Ambient temperature

With sulfuric acid; In diethyl ether;

Reference yield:

1,7,7-trimethyl-6-endo-phenylbicyclo<2.2.1>hept-2-yl-exo-methoxypropionamide (128321-79-9) → 1,7,7-trimethyl-6-endo-phenylbicyclo<2.2.1>hept-2-yl-exo-amine hydrochloride

Guidance literature:

With hydrogenchloride; In ethanol; for 48h; Yield given; Heating;

upstream raw materials:

3-Methoxypropionitrile

5,5,6-trimethyl-2-phenylbicyclo<2.2.1>heptan-2-endo-ol

5,5,6-trimethylbicyclo[2.2.1]heptan-2-one

Refernces