Cys(PMB)-Pro-Leu-Gly-NH₂

Base Information

• Chemical Name: Cys(PMB)-Pro-Leu-Gly-NH₂
• CAS No.: 82215-15-4
• Molecular Formula: C₂₄H₃₇N₅O₅S
• Molecular Weight: 507.654
• Mol file: 82215-15-4.mol

Synonyms:

Chemical Property of Cys(PMB)-Pro-Leu-Gly-NH₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cys(PMB)-Pro-Leu-Gly-NH₂

There total 4 articles about Cys(PMB)-Pro-Leu-Gly-NH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Boc-Cys(PMB)-Pro-Leu-Gly-NH2 (82215-17-6) → Cys(PMB)-Pro-Leu-Gly-NH2 (82215-15-4)

Guidance literature:

With trifluoroacetic acid; In various solvent(s);

DOI:10.1016/S0040-4039(00)86771-4

Reference yield:

melanostatin (2002-44-0) → Cys(PMB)-Pro-Leu-Gly-NH2 (82215-15-4)

Guidance literature:

Multi-step reaction with 2 steps

2: trifluoracetic acid / various solvent(s)

With trifluoroacetic acid; In various solvent(s);

DOI:10.1016/S0040-4039(00)86771-4

Reference yield:

N-(tert-butyloxycarbonyl)-S-(4-methoxybenzyl)cysteine (18942-46-6,58290-35-0) → Cys(PMB)-Pro-Leu-Gly-NH2 (82215-15-4)

Guidance literature:

Multi-step reaction with 3 steps

1: DCC

3: trifluoracetic acid / various solvent(s)

With dicyclohexyl-carbodiimide; trifluoroacetic acid; In various solvent(s);

DOI:10.1016/S0040-4039(00)86771-4

upstream raw materials:

Boc-Cys(PMB)-Pro-Leu-Gly-NH₂

melanostatin

N-(tert-butyloxycarbonyl)-S-(4-methoxybenzyl)cysteine

Boc-Cys(PMB)-OTcp

Downstream raw materials:

Boc-Tan-Cys(PMB)-Pro-Leu-Gly-NH₂

Boc-Can-Cys(PMB)-Pro-Leu-Gly-NH₂

Refernces