trans-5-(4-nitro-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid amide

Base Information

• Chemical Name: trans-5-(4-nitro-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid amide
• CAS No.: 70671-36-2
• Molecular Formula: C₁₀H₉N₃O₄
• Molecular Weight: 235.199
• Mol file: 70671-36-2.mol

Synonyms:

Chemical Property of trans-5-(4-nitro-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-5-(4-nitro-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid amide

There total 1 articles about trans-5-(4-nitro-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isocyanoacetamide (51641-98-6) + 4-nitrobenzaldehdye (555-16-8) → trans-5-(4-nitro-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid amide (70671-36-2)

Guidance literature:

With potassium hydroxide; In methanol; at 10 - 15 ℃; for 2h;

DOI:10.1055/s-1979-28626

Reference yield:

trans-5-(4-nitro-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid amide (70671-36-2) → (2RS,3SR)-2-amino-3-hydroxy-3-(4-nitro-phenyl)-propionic acid (5872-74-2,5872-75-3,10098-38-1,17580-62-0,28908-09-0,50730-77-3,110772-43-5,119934-01-9,129446-45-3,135635-69-7)

Guidance literature:

With hydrogenchloride;

DOI:10.1055/s-1979-28626

upstream raw materials:

isocyanoacetamide

4-nitrobenzaldehdye

Downstream raw materials:

(2RS,3SR)-2-amino-3-hydroxy-3-(4-nitro-phenyl)-propionic acid