BUTTPARK 21\02-64

Base Information

• Chemical Name: BUTTPARK 21\02-64
• CAS No.: 10493-27-3
• Molecular Formula: C9H10N4O2
• Molecular Weight: 206.204
• Mol file: 10493-27-3.mol

Synonyms:

Chemical Property of BUTTPARK 21\02-64

Chemical Property:

• Melting Point: 206-207 °C(Solv: ethanol (64-17-5))
• Boiling Point: 390.1±52.0 °C(Predicted)
• PKA: 4.24±0.10(Predicted)
• PSA: 72.92000
• Density: 1.283±0.06 g/cm3(Predicted)
• LogP: 0.88390

Purity/Quality:

99% ^*data from raw suppliers

5-(3,4-Dimethoxyphenyl)-2H-tetrazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BUTTPARK 21\02-64

There total 5 articles about BUTTPARK 21\02-64 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

veratronitrile (2024-83-1) → (3',4'-dimethoxyphenyl)-1H-tetrazole (10493-27-3)

Guidance literature:

With sodium azide; N,N-diisopropylethylammonium acetate; at 90 ℃; for 0.5h; Green chemistry;

DOI:10.1080/00397911.2017.1281421

Reference yield: 80.0%

3,4-dimethoxy-benzaldehyde (120-14-9) → (3',4'-dimethoxyphenyl)-1H-tetrazole (10493-27-3)

Guidance literature:

With bismuth(lll) trifluoromethanesulfonate; sodium azide; acetylhydroxamic acid; In N,N-dimethyl-formamide; at 120 ℃; for 24h;

DOI:10.1055/s-0032-1318108

Reference yield: 78.0%

veratronitrile (2024-83-1) → 5-(3,4-Dimethoxyphenyl)tetrazole (10493-27-3)

Guidance literature:

With sodium azide; ammonium chloride; In N,N-dimethyl-formamide; for 17h; Heating;

DOI:10.1021/jm00378a007

upstream raw materials:

veratronitrile

3,4-dimethoxy-benzaldehyde

3,4-Dimethoxy-benzaldehyde oxime

Downstream raw materials:

[5-(3,4-Dihydroxy-phenyl)-tetrazol-2-yl]-acetic acid

[5-(3,4-Dimethoxy-phenyl)-tetrazol-2-yl]-acetic acid

5-(3,4-dimethoxyphenyl)-2-[7-[5-(3,4-dimethoxyphenyl)tetrazol-1-yl]heptyl]tetrazole

2-[3-(4,6-bis-trichloromethyl-s-triazin-2-yl)phenyl]-5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazole

Refernces

• 1、 Pusinov, G. L.,Ishmetova, R. I.,Kitaeva, V. G.,Beresnev, D. G.. "SYNTHESIS OF SOME 5-ARYL(HETARYL)TETRAZOLES BY ULTRASONICATION". . p. 1192 - 1194. Retrieved 1994.
• 2、 Fatima, Itrat,Zafar, Humaira,Khan, Khalid Mohammed,Saad, Syed Muhammad,Javaid, Sumaira,Perveen, Shahnaz,Choudhary, M. Iqbal. "Synthesis, molecular docking and xanthine oxidase inhibitory activity of 5-aryl-1H-tetrazoles". . p. 201 - 211. Retrieved 2018/05/24.
• 3、 Khan, Khalid Mohammed,Fatima, Itrat,Saad, Syed Muhammad,Taha, Muhammad,Voelter, Wolfgang. "An efficient one-pot protocol for the conversion of benzaldehydes into tetrazole analogs". . p. 523 - 524. Retrieved 2016/01/20.