Technology Process of 3-amino-5-methoxyphenylboronic acid
There total 4 articles about 3-amino-5-methoxyphenylboronic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3-bromo-5-methoxyaminobenzene; bis(pinacol)diborane;
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate;
In
dimethyl sulfoxide;
at 80 ℃;
for 18h;
Inert atmosphere;
water;
With
sodium periodate; ammonium chloride;
In
methanol;
at 20 ℃;
for 18h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: methanol / 2 h / 45 °C
2.1: palladium on activated charcoal; hydrogen / methanol; acetone / 3 h / 20 °C
3.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 18 h / 80 °C / Inert atmosphere
3.2: 18 h / 20 °C
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; palladium on activated charcoal; hydrogen; potassium acetate;
In
methanol; dimethyl sulfoxide; acetone;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: N-Bromosuccinimide; sulfuric acid / 0.5 h / 80 - 90 °C
2.1: methanol / 2 h / 45 °C
3.1: palladium on activated charcoal; hydrogen / methanol; acetone / 3 h / 20 °C
4.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 18 h / 80 °C / Inert atmosphere
4.2: 18 h / 20 °C
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; N-Bromosuccinimide; sulfuric acid; palladium on activated charcoal; hydrogen; potassium acetate;
In
methanol; dimethyl sulfoxide; acetone;
