4-chloro-3-ethoxytoluene

Base Information

• Chemical Name: 4-chloro-3-ethoxytoluene
• CAS No.: 3031-86-5
• Molecular Formula: C₉H₁₁ClO
• Molecular Weight: 170.639
• Mol file: 3031-86-5.mol

Synonyms:

Chemical Property of 4-chloro-3-ethoxytoluene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-chloro-3-ethoxytoluene

There total 1 articles about 4-chloro-3-ethoxytoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-5-methylphenol (615-74-7) + ethyl iodide (75-03-6) → 4-chloro-3-ethoxytoluene (3031-86-5) + 2-chloro-5-methylanisole (73909-16-7)

Guidance literature:

Reference yield:

4-chloro-3-ethoxytoluene (3031-86-5) → 5-nitro-2-(4-oxocyclohexylamino)-N-(1,3-benzodioxol-5-ylmethyl)benzamide (247566-80-9)

Guidance literature:

Multi-step reaction with 6 steps

2: N-methyl-acetamide

3: hydrazine hydrate / ethanol

5: pyridine

6: silica gel / dichloromethane; acetonitrile

With hydrazine hydrate; silica gel; In pyridine; N-methyl-acetamide; ethanol; dichloromethane; acetonitrile;

Reference yield:

4-chloro-3-ethoxytoluene (3031-86-5) → N-(4-chloro-3-methoxybenzyl)-2-fluoro-5-vinylbenzamide (247570-15-6)

Guidance literature:

Multi-step reaction with 5 steps

2: N-methyl-acetamide

3: hydrazine hydrate / ethanol

5: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene

With hydrazine hydrate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N-methyl-acetamide; ethanol; toluene;

upstream raw materials:

2-chloro-5-methylphenol

ethyl iodide

Downstream raw materials:

4-chloro-3-ethoxybenzyl bromide

4-(bromomethyl)-1-chloro-2-methoxybenzene

2-{[4-chloro-3-(methyloxy)phenyl]methyl}-1H-isoindole-1,3(2H)-dione

5-bromo-N-(4-chloro-3-methoxybenzyl)-2-fluorobenzamide

Refernces