N'-(2,4-dinitrophenyl)acetohydrazide

Base Information

• Chemical Name: N'-(2,4-dinitrophenyl)acetohydrazide
• CAS No.: 2719-07-5
• Molecular Formula: C8H8 N4 O5
• Molecular Weight: 240.175
• European Community (EC) Number: 633-068-0
• NSC Number: 400300
• UNII: WA39NLB8HQ
• DSSTox Substance ID: DTXSID90181655
• Nikkaji Number: J86.171E
• Wikidata: Q83052284
• Mol file: 2719-07-5.mol

Synonyms:N'-(2,4-dinitrophenyl)acetohydrazide;ACETIC ACID, 2-(2,4-DINITROPHENYL)HYDRAZIDE;WA39NLB8HQ;2719-07-5;NSC 400300;NSC-400300;AI3-16237;NSC400300;UNII-WA39NLB8HQ;DTXSID90181655;NYZGFEVPHFYXKA-UHFFFAOYSA-N;STK144637;AKOS003615046;N-(2,4-dinitrophenyl)-N'-acetylhydrazine;ACETIC ACID, 2,4-DINITROPHENYLHYDRAZIDE;Acetic acid, 2-(2,4-dinitro-phenyl)hydrazide;Acetic acid, 2-(2,4-dinitrophenyl) hydrazide

Chemical Property of N'-(2,4-dinitrophenyl)acetohydrazide

Chemical Property:

• XLogP3: 1.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 240.04946937
• Heavy Atom Count: 17
• Complexity: 323

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NNC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-]

Technology Process of N'-(2,4-dinitrophenyl)acetohydrazide

There total 12 articles about N'-(2,4-dinitrophenyl)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

magnesium acetate (142-72-3,92123-19-8) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → acetic acid-[N'-(2,4-dinitro-phenyl)-hydrazide] (2719-07-5)

Guidance literature:

In acetic acid; for 0.5h; chemoselective reaction; Reflux;

DOI:10.3184/030823410X12746305905926

Reference yield: 95.0%

acetic acid (64-19-7,77671-22-8) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → acetic acid-[N'-(2,4-dinitro-phenyl)-hydrazide] (2719-07-5)

Guidance literature:

With zinc(II) acetate dihydrate; for 0.0833333h; chemoselective reaction; Microwave irradiation; Sealed tube;

Reference yield:

(2,4-dinitro-phenyl)-hydrazine (119-26-6) → acetic acid-[N'-(2,4-dinitro-phenyl)-hydrazide] (2719-07-5)

Guidance literature:

With ethanol; sulfuric acid; acetic acid;

DOI:10.1021/ja01307a052

upstream raw materials:

malonic acid mono-[N'-(2,4-dinitro-phenyl)-hydrazide]

acetic acid

(2,4-dinitro-phenyl)-hydrazine

C₈H₇BrN₄O₄

Downstream raw materials:

1-Deuterio-2,4-dinitrobenzene

meta-dinitrobenzene

C₈H₆N₄O₅

N-(2,4-dinitrophenyl)-acetohydrazonyl chloride

Refernces

• 1、 Brahmachari,Laskar,Sarkar. "A green approach to chemoselective N-acetylation of amines using catalytic amount of zinc acetate in acetic acid under microwave irradiation". experimental part. p. 1274 - 1281. Retrieved 2010/12/24.
• 2、 Uchiyama, Shigehisa,Matsushima, Erika,Aoyagi, Shohei,Ando, Masanori. "Simultaneous determination of C1-C4 carboxylic acids and aldehydes using 2,4-dinitrophenylhydrazine-impregnated silica gel and high-performance liquid chromatography". . p. 5849 - 5854. Retrieved 2007/10/03.