5-tert-Butyl-3-phenylsulfanyl-[2,2']bifuranyl

Base Information

• Chemical Name: 5-tert-Butyl-3-phenylsulfanyl-[2,2']bifuranyl
• CAS No.: 127459-18-1
• Molecular Formula: C₁₈H₁₈O₂S
• Molecular Weight: 298.406
• Mol file: 127459-18-1.mol

Synonyms:

Chemical Property of 5-tert-Butyl-3-phenylsulfanyl-[2,2']bifuranyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-tert-Butyl-3-phenylsulfanyl-[2,2']bifuranyl

There total 4 articles about 5-tert-Butyl-3-phenylsulfanyl-[2,2']bifuranyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiophenol (108-98-5) → 5-tert-Butyl-3-phenylsulfanyl-[2,2']bifuranyl (127459-18-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 89 percent / Et₃N / CCl₄ / 2 h / Ambient temperature

2: 1.) chlorosuccinimide, 2.) Et₃N / 1.) benzene, 0 deg C, 1 h, then room temp., 2 h, 2.) benzene, 0 deg C, 2 h, then room temp., 2 h

With N-chloro-succinimide; triethylamine; In tetrachloromethane;

DOI:10.1248/cpb.37.2914

Reference yield:

3-phenylsulfanyl-propionaldehyde (27098-65-3) → 5-tert-Butyl-3-phenylsulfanyl-[2,2']bifuranyl (127459-18-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) chlorosuccinimide, 2.) Et₃N / 1.) benzene, 0 deg C, 1 h, then room temp., 2 h, 2.) benzene, 0 deg C, 2 h, then room temp., 2 h

With N-chloro-succinimide; triethylamine;

DOI:10.1248/cpb.37.2914

Reference yield:

2-furancarbonyl chloride (527-69-5) + β-thiophenylacrolein (80227-71-0) + methyllithium (917-54-4) → 5-tert-Butyl-3-phenylsulfanyl-[2,2']bifuranyl (127459-18-1)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1248/cpb.37.2914

upstream raw materials:

2-furancarbonyl chloride

β-thiophenylacrolein

methyllithium

N,N-dimethyl-2-furfurylcarboxamide

Refernces