1-(2-methyl-3,5-dinitro-phenyl)-ethanone

Base Information

• Chemical Name: 1-(2-methyl-3,5-dinitro-phenyl)-ethanone
• CAS No.: 5285-37-0
• Molecular Formula: C₉H₈N₂O₅
• Molecular Weight: 224.173
• Mol file: 5285-37-0.mol

Synonyms:

Chemical Property of 1-(2-methyl-3,5-dinitro-phenyl)-ethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-methyl-3,5-dinitro-phenyl)-ethanone

There total 3 articles about 1-(2-methyl-3,5-dinitro-phenyl)-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-3,5-dinitro-benzoyl chloride (39614-85-2) + diethyl ethoxymagnesium malonate → 1-(2-methyl-3,5-dinitro-phenyl)-ethanone (5285-37-0)

Guidance literature:

With diethyl ether; ethanol; Kochen des Reaktionsprodukts mit wss. H₂SO₄ und Essigsaeure;

DOI:10.1021/ja01171a507

Reference yield:

3,5-dinitro-o-toluic acid (28169-46-2) → 1-(2-methyl-3,5-dinitro-phenyl)-ethanone (5285-37-0)

Guidance literature:

Multi-step reaction with 3 steps

1: phosphorus (V)-chloride

2: diethyl ether; ethanolic sodium ethylate

3: aqueous sulfuric acid

With diethyl ether; phosphorus pentachloride; sulfuric acid; sodium ethanolate;

DOI:10.1021/jo01155a010

Reference yield:

2-methyl-3,5-dinitro-benzoyl chloride (39614-85-2) → 1-(2-methyl-3,5-dinitro-phenyl)-ethanone (5285-37-0)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether; ethanolic sodium ethylate

2: aqueous sulfuric acid

With diethyl ether; sulfuric acid; sodium ethanolate;

DOI:10.1021/jo01155a010

upstream raw materials:

2-methyl-3,5-dinitro-benzoyl chloride

3,5-dinitro-o-toluic acid