C₂₂H₁₉NO

Base Information

• Chemical Name: C₂₂H₁₉NO
• CAS No.: 869485-31-4
• Molecular Formula: C₂₂H₁₉NO
• Molecular Weight: 313.399
• Mol file: 869485-31-4.mol

Synonyms:

Chemical Property of C₂₂H₁₉NO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₁₉NO

There total 6 articles about C₂₂H₁₉NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

5-(2-but-3-en-1-ynyl-phenyl)-pent-4-ynal (869485-30-3) + N-benzyl hydroxylalmine (622-30-0) → C22H19NO (869485-31-4)

Guidance literature:

With methanol;

DOI:10.1016/j.tetlet.2005.08.125

Reference yield:

1-bromo-2-but-3-en-1-ynyl-benzene (869485-28-9) → C22H19NO (869485-31-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 68 percent / Pd(PPh₃)4; n-BuNH₂

2: 65 percent / PCC / CH₂Cl₂

3: 85 percent / methanol

With methanol; tetrakis(triphenylphosphine) palladium⁽⁰⁾; N-butylamine; pyridinium chlorochromate; In dichloromethane; 1: Shongashira coupling;

DOI:10.1016/j.tetlet.2005.08.125

Reference yield:

5-(2-but-3-en-1-ynyl-phenyl)-pent-4-yn-1-ol (869485-29-0) → C22H19NO (869485-31-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / PCC / CH₂Cl₂

2: 85 percent / methanol

With methanol; pyridinium chlorochromate; In dichloromethane;

DOI:10.1016/j.tetlet.2005.08.125

upstream raw materials:

5-(2-but-3-en-1-ynyl-phenyl)-pent-4-ynal

N-benzyl hydroxylalmine

1-bromo-2-but-3-en-1-ynyl-benzene

5-(2-but-3-en-1-ynyl-phenyl)-pent-4-yn-1-ol

Refernces