2-O-hexylglycerol

Base Information

• Chemical Name: 2-O-hexylglycerol
• CAS No.: 100078-38-4
• Molecular Formula: C₉H₂₀O₃
• Molecular Weight: 176.256
• Mol file: 100078-38-4.mol

Synonyms:

Chemical Property of 2-O-hexylglycerol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-O-hexylglycerol

There total 5 articles about 2-O-hexylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,3-dihydroxypropyl hexanoate (502-53-4) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → hexyl glycerol (106972-45-6) + 2-O-hexylglycerol (100078-38-4)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; at 120 ℃; for 16h; under 37503.8 Torr; regioselective reaction; Autoclave;

DOI:10.1039/c3gc36907b

Reference yield: 73.0%

methyl hexanoate (106-70-7) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → hexyl glycerol (106972-45-6) + 2-O-hexylglycerol (100078-38-4)

Guidance literature:

With 5%-palladium/activated carbon; camphor-10-sulfonic acid; hydrogen; at 120 ℃; for 16h; under 37503.8 Torr; regioselective reaction; Autoclave;

DOI:10.1039/c3gc36907b

Reference yield:

hexanal (66-25-1) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → 1,3-bishexyloxy-2-propanol (34834-51-0) + hexyl glycerol (106972-45-6) + (+/-)-1,2-di-O-hexyl-sn-glycerol (110033-67-5) + 2-O-hexylglycerol (100078-38-4)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; at 200 ℃; for 8h; under 51716.2 Torr; Inert atmosphere;

upstream raw materials:

hexanal

glycerol

hexan-1-ol

2,3-dihydroxypropyl hexanoate

Refernces

• 1、 Sutter, Marc,Dayoub, Wissam,Metay, Estelle,Raoul, Yann,Lemaire, Marc. "1-O-Alkyl (di)glycerol ethers synthesis from methyl esters and triglycerides by two pathways: Catalytic reductive alkylation and transesterification/reduction". supporting information. p. 786 - 797. Retrieved 2013/04/24.
• 2、 Gaudin, Pierrick,Jacquot, Roland,Marion, Philippe,Pouilloux, Yannick,Jér?me, Fran?ois. "Acid-catalyzed etherification of glycerol with long-alkyl-chain alcohols". experimental part. p. 719 - 722. Retrieved 2012/05/20.