Technology Process of [(2E,4E,8Z)-(R)-6-(tert-Butyl-diphenyl-silanyloxy)-12-methoxycarbonyl-dodeca-2,4,8-trienyl]-triphenyl-phosphonium; bromide
There total 9 articles about [(2E,4E,8Z)-(R)-6-(tert-Butyl-diphenyl-silanyloxy)-12-methoxycarbonyl-dodeca-2,4,8-trienyl]-triphenyl-phosphonium; bromide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: lithium hexamethyldisilazide (LiHMDS) / tetrahydrofuran; hexamethylphosphoric acid triamide
4: aq. acid
5: lead tetraacetate / CH2Cl2 / -78 °C
7: 2.) sodium borohydride/ceric chloride / 2.) isopropanol
8: 1) DIPHOS, carbon tetrabromide / 2) triphenylphosphine
With
lead(IV) acetate; sodium tetrahydroborate; ceric chloride; carbon tetrabromide; temephos; lithium hexamethyldisilazane;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane;
DOI:10.1016/0040-4039(84)80003-9
- Guidance literature:
-
Multi-step reaction with 7 steps
3: aq. acid
4: lead tetraacetate / CH2Cl2 / -78 °C
6: 2.) sodium borohydride/ceric chloride / 2.) isopropanol
7: 1) DIPHOS, carbon tetrabromide / 2) triphenylphosphine
With
lead(IV) acetate; sodium tetrahydroborate; ceric chloride; carbon tetrabromide; temephos;
In
dichloromethane;
DOI:10.1016/0040-4039(84)80003-9
- Guidance literature:
-
Multi-step reaction with 7 steps
3: aq. acid
4: lead tetraacetate / CH2Cl2 / -78 °C
6: 2.) sodium borohydride/ceric chloride / 2.) isopropanol
7: 1) DIPHOS, carbon tetrabromide / 2) triphenylphosphine
With
lead(IV) acetate; sodium tetrahydroborate; ceric chloride; carbon tetrabromide; temephos;
In
dichloromethane;
DOI:10.1016/0040-4039(84)80003-9