Technology Process of Acetic acid (3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((1S,7S)-4-formyl-7-methyl-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-1-yloxy)-tetrahydro-pyran-3-yl ester
There total 2 articles about Acetic acid (3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((1S,7S)-4-formyl-7-methyl-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-1-yloxy)-tetrahydro-pyran-3-yl ester which
guide to synthetic route it.
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synthetic route:
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72963-60-1,107035-48-3
Acetic acid (3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-((1S,7S)-4-formyl-7-methyl-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-1-yloxy)-tetrahydro-pyran-3-yl ester
- Guidance literature:
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With
sodium methylate;
In
methanol;
DOI:10.1016/S0040-4020(01)81508-8
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72963-55-4,80734-66-3
(1S,4aS,7R,7aR)-7-methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1H,4aH,5H,6H,7H,7aH-cyclopenta[c] pyran-4-aldehyde
- Guidance literature:
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With
pyridine;
Yield given;
Ambient temperature;
DOI:10.1248/cpb.28.1730
- Guidance literature:
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Multi-step reaction with 3 steps
1: 912.4 mg / 2-methyl-2-butene, sodium chlorite, sodium dihydrogen phosphate / 2-methyl-propan-2-ol; H2O / 40 h / Ambient temperature
2: 95.8 mg / diethyl ether; methanol / 0.5 h / 0 - 20 °C
3: 301.0 mg / 0.26 N NaOMe / methanol / 4 h / Ambient temperature
With
sodium chlorite; sodium dihydrogen phosphate; 2-methyl-but-2-ene; sodium methylate;
In
methanol; diethyl ether; water; tert-butyl alcohol;