ethyl (2E,4E)-hexa-2,4-dien-1-yl fumarate

Base Information

• Chemical Name: ethyl (2E,4E)-hexa-2,4-dien-1-yl fumarate
• CAS No.: 160386-62-9
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.257
• Mol file: 160386-62-9.mol

Synonyms:

Chemical Property of ethyl (2E,4E)-hexa-2,4-dien-1-yl fumarate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of ethyl (2E,4E)-hexa-2,4-dien-1-yl fumarate

There total 1 articles about ethyl (2E,4E)-hexa-2,4-dien-1-yl fumarate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 4.0%

(E)-4-ethoxy-4-oxobut-2-enoic acid (2459-05-4) + (1S,2S)-2-Hydroxymethyl-cyclohexanecarboxylic acid (2E,4E)-hexa-2,4-dienyl ester → ethyl (2E,4E)-hexa-2,4-dien-1-yl fumarate (160386-62-9) + (E)-But-2-enedioic acid ethyl ester (1S,2S)-2-[((2E,4E)-hexa-2,4-dienyl)oxycarbonyl]-cyclohexylmethyl ester

Guidance literature:

With triethylamine; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(98)01829-2

Reference yield:

ethyl (2E,4E)-hexa-2,4-dien-1-yl fumarate (160386-62-9) → (1S,2S,3R,6S)-3-Hydroxymethyl-6-methyl-cyclohex-4-ene-1,2-dicarboxylic acid 1-ethyl ester

Guidance literature:

With pig liver esterase; Yield given. Multistep reaction; 1.) toluene, 100 deg C, 24 h, 2.) phosphate buffer, pH=8, toluene, 27 deg C, 24 h;

DOI:10.1016/0040-4039(94)80019-7

upstream raw materials:

(E)-4-ethoxy-4-oxobut-2-enoic acid

Refernces