Technology Process of (Z)-1-(2,3,5,6-tetramethoxyphenyl)-8-heptadecene
There total 4 articles about (Z)-1-(2,3,5,6-tetramethoxyphenyl)-8-heptadecene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: mCPBA / 2 h / Ambient temperature
2: aq. KOH / ethanol / 2 h / 50 °C
3: 94 percent / NaH / dimethylformamide / 1 h / Ambient temperature
4: 1.) HMPA, n-BuLi / 1.) THF, hexane, -40 deg C, 30 min, then -40 to -10 deg C, 1 h, -10 deg C, 1h, 2.) THF, hexane, overnight
With
N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hydroxide; n-butyllithium; sodium hydride; 3-chloro-benzenecarboperoxoic acid;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(98)00927-2
- Guidance literature:
-
Multi-step reaction with 3 steps
1: aq. KOH / ethanol / 2 h / 50 °C
2: 94 percent / NaH / dimethylformamide / 1 h / Ambient temperature
3: 1.) HMPA, n-BuLi / 1.) THF, hexane, -40 deg C, 30 min, then -40 to -10 deg C, 1 h, -10 deg C, 1h, 2.) THF, hexane, overnight
With
N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hydroxide; n-butyllithium; sodium hydride;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(98)00927-2
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 94 percent / NaH / dimethylformamide / 1 h / Ambient temperature
2: 1.) HMPA, n-BuLi / 1.) THF, hexane, -40 deg C, 30 min, then -40 to -10 deg C, 1 h, -10 deg C, 1h, 2.) THF, hexane, overnight
With
N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; sodium hydride;
In
N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(98)00927-2
