C₂₄H₃₁NO₅

Base Information

• Chemical Name: C₂₄H₃₁NO₅
• CAS No.: 1418218-93-5
• Molecular Formula: C₂₄H₃₁NO₅
• Molecular Weight: 413.514
• Mol file: 1418218-93-5.mol

Synonyms:

Chemical Property of C₂₄H₃₁NO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₃₁NO₅

There total 8 articles about C₂₄H₃₁NO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C7H6I2O (1418218-67-3) → C24H31NO5 (1418218-93-5)

Guidance literature:

Multi-step reaction with 6 steps

1: dichloromethane / 0.5 h

2: sodium azide / N,N-dimethyl-formamide / 20 °C

3: triphenylphosphine / water; tetrahydrofuran

4: chloroform / 20 °C

5: tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; copper(l) iodide / 3 h

6: tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; copper(l) iodide

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium azide; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; chloroform; water; N,N-dimethyl-formamide; 5: |Sonogashira Cross-Coupling / 6: |Sonogashira Cross-Coupling;

DOI:10.1016/j.tetlet.2012.11.102

Reference yield:

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → C24H31NO5 (1418218-93-5)

Guidance literature:

Multi-step reaction with 9 steps

1: sodium periodate; potassium iodide / water; methanol

2: potassium iodide; sodium nitrite; sulfuric acid

3: dimethyl sulfide borane / tetrahydrofuran

4: dichloromethane / 0.5 h

5: sodium azide / N,N-dimethyl-formamide / 20 °C

6: triphenylphosphine / water; tetrahydrofuran

7: chloroform / 20 °C

8: tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; copper(l) iodide / 3 h

9: tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; copper(l) iodide

With sodium periodate; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium azide; sulfuric acid; dimethyl sulfide borane; triethylamine; triphenylphosphine; potassium iodide; sodium nitrite; In tetrahydrofuran; methanol; dichloromethane; chloroform; water; N,N-dimethyl-formamide; 8: |Sonogashira Cross-Coupling / 9: |Sonogashira Cross-Coupling;

DOI:10.1016/j.tetlet.2012.11.102

Reference yield:

4-amino-3-iodobenzoic acid (2122-63-6) → C24H31NO5 (1418218-93-5)

Guidance literature:

Multi-step reaction with 8 steps

1: potassium iodide; sodium nitrite; sulfuric acid

2: dimethyl sulfide borane / tetrahydrofuran

3: dichloromethane / 0.5 h

4: sodium azide / N,N-dimethyl-formamide / 20 °C

5: triphenylphosphine / water; tetrahydrofuran

6: chloroform / 20 °C

7: tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; copper(l) iodide / 3 h

8: tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; copper(l) iodide

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium azide; sulfuric acid; dimethyl sulfide borane; triethylamine; triphenylphosphine; potassium iodide; sodium nitrite; In tetrahydrofuran; dichloromethane; chloroform; water; N,N-dimethyl-formamide; 7: |Sonogashira Cross-Coupling / 8: |Sonogashira Cross-Coupling;

DOI:10.1016/j.tetlet.2012.11.102

upstream raw materials:

4-amino-benzoic acid

4-amino-3-iodobenzoic acid

3,4-diiodobenzoic acid

C₇H₆I₂O

Downstream raw materials:

C₂₅H₃₃NO₇S

C₂₅H₃₃NO₇S

Refernces