2-oxo-3-phenyl-propanal

Base Information

• Chemical Name: 2-oxo-3-phenyl-propanal
• CAS No.: 56485-04-2
• Molecular Formula: C9H8 O2
• Molecular Weight: 148.161
• Mol file: 56485-04-2.mol

Synonyms:Pyruvaldehyde,phenyl- (6CI,7CI); Benzylglyoxal; NSC 337791

Chemical Property of 2-oxo-3-phenyl-propanal

Chemical Property:

• Vapor Pressure: 0.0325mmHg at 25°C
• Boiling Point: 243.2°Cat760mmHg
• Flash Point: 91.2°C
• PSA: 34.14000
• Density: 1.112g/cm³
• LogP: 0.99710

Purity/Quality:

98%min ^*data from raw suppliers

2-OXO-3-PHENYL-PROPANAL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-oxo-3-phenyl-propanal

There total 11 articles about 2-oxo-3-phenyl-propanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-oxo-3-(phenyl)propionic acid (156-06-9) → benzylglyoxal (56485-04-2)

Guidance literature:

2-oxo-3-(phenyl)propionic acid; With pyridine; acetic anhydride; at 20 ℃; for 15h;

With hydrogenchloride; In dichloromethane; water;

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2-acetoxy-2-phenylacetyl chloride (1638-63-7) → benzylglyoxal (56485-04-2) + benzaldehyde (100-52-7)

Guidance literature:

With diethyl ether; etheric solution; Behandeln des Reaktionsprodukts mit verd. wss. Schwefelsaeure;

DOI:10.1039/jr9370001913

Reference yield:

3-phenyl methylglyoxal dimethyl acetal (77252-94-9) → benzylglyoxal (56485-04-2)

Guidance literature:

With water; toluene-4-sulfonic acid; In tetrahydrofuran; for 20h; Heating;

DOI:10.1021/jo00014a038

upstream raw materials:

diazomethane

2-acetoxy-2-phenylacetyl chloride

diethoxyacetic acid piperidinyl amide

benzylmagnesium chloride

Downstream raw materials:

1,1-diethoxy-3-phenylpropane-2-one

9-Methoxymethyl-1-phenylacetyl-9H-β-carboline-3-carboxylic acid ethyl ester

6-Bromo-9-methoxymethyl-1-phenylacetyl-9H-β-carboline-3-carboxylic acid ethyl ester

2-benzyl-8-benzyl-6-(phenyl)imidazo[1,2-a]pyrazin-3(7H)-one

Refernces

• 1、 Shereshovets, V. V.,Korotaeva, N. M.,Vorob'ev, A. S.,Komissarov, V. D.,Furlei, I. I.. "Oxidation of diazo compounds by triphenyl phosphite ozonide. Quenching of singlet oxygen by diazo compounds". . p. 1479 - 1483. Retrieved 2007/10/02.