p-tolyl 2-phenyl-2-propyl sulfone

Base Information

• Chemical Name: p-tolyl 2-phenyl-2-propyl sulfone
• CAS No.: 71376-57-3
• Molecular Formula: C₁₆H₁₈O₂S
• Molecular Weight: 274.384
• Mol file: 71376-57-3.mol

Synonyms:

Chemical Property of p-tolyl 2-phenyl-2-propyl sulfone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-tolyl 2-phenyl-2-propyl sulfone

There total 4 articles about p-tolyl 2-phenyl-2-propyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → p-tolyl 2-phenyl-2-propyl sulfone (71376-57-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / water; diethyl ether / 20 h / 20 °C

2: silver fluoride; sodium persulfate / acetonitrile; water / 24 h / 100 °C / Inert atmosphere; Schlenk technique

With sodium persulfate; silver fluoride; sodium hydroxide; In diethyl ether; water; acetonitrile;

DOI:10.1246/BCSJ.20200393

Reference yield:

methyl bromide (74-83-9) + 1-methyl-4-[(1-phenylethyl)sulfonyl]benzene (24422-77-3) → p-tolyl 2-phenyl-2-propyl sulfone (71376-57-3)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; tetrabutylammomium bromide; In methanol;

DOI:10.1055/s-1979-28720

Reference yield:

p-toluene sulfinic acid (536-57-2) + 1-methyl-1-phenylethyl alcohol (617-94-7) → p-tolyl 2-phenyl-2-propyl sulfone (71376-57-3)

Guidance literature:

With hydrogenchloride; acetic acid;

upstream raw materials:

p-toluene sulfinic acid

1-methyl-1-phenylethyl alcohol

toluene-4-sulfinic acid-(1-methyl-1-phenyl-ethyl ester)

methyl bromide

Refernces