1-(2-fluoro-6-methylphenyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine

Base Information

• Chemical Name: 1-(2-fluoro-6-methylphenyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine
• CAS No.: 1315692-86-4
• Molecular Formula: C₁₃H₂₂FNSi₂
• Molecular Weight: 267.494
• Mol file: 1315692-86-4.mol

Synonyms:

Chemical Property of 1-(2-fluoro-6-methylphenyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-fluoro-6-methylphenyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine

There total 2 articles about 1-(2-fluoro-6-methylphenyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-fluoro-6-methylaniline (443-89-0) → 1-(2-fluoro-6-methylphenyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine (1315692-86-4)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethylammonium chloride; zinc(II) iodide / Inert atmosphere; Heating

2: Heating

With N,N-dimethylammonium chloride; zinc(II) iodide;

DOI:10.1055/s-0030-1260019

Reference yield:

C15H29FN2Si2 → 1-(2-fluoro-6-methylphenyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine (1315692-86-4)

Guidance literature:

Heating;

DOI:10.1055/s-0030-1260019

Reference yield:

1-(2-fluoro-6-methylphenyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine (1315692-86-4) → C13H23BFNO2Si2

Guidance literature:

Multi-step reaction with 2 steps

1: 2,2,6,6-tetramethylpiperidinyl-lithium / tetrahydrofuran; hexane / Inert atmosphere; Cooling

2: water; ammonium chloride / 0.5 h / 20 °C

With 2,2,6,6-tetramethylpiperidinyl-lithium; water; ammonium chloride; In tetrahydrofuran; hexane;

DOI:10.1055/s-0030-1260019

upstream raw materials:

2-fluoro-6-methylaniline

Downstream raw materials:

2-fluoro-6-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Refernces