Cyclohex-1-enecarboximidic acid ethyl ester

Base Information

• Chemical Name: Cyclohex-1-enecarboximidic acid ethyl ester
• CAS No.: 1019020-13-3
• Molecular Formula: C₉H₁₅NO
• Molecular Weight: 153.224
• Mol file: 1019020-13-3.mol

Synonyms:

Chemical Property of Cyclohex-1-enecarboximidic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclohex-1-enecarboximidic acid ethyl ester

There total 2 articles about Cyclohex-1-enecarboximidic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclohex-1-enecarbonitrile (1855-63-6) → Cyclohex-1-enecarboximidic acid ethyl ester (1019020-13-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / nBu₄NHSO₄, 30percent H₂O₂, 20percent NaOH / CH₂Cl₂ / 4 h / 0 °C

2: 1,2-dichloro-ethane / 18 h / Ambient temperature

With sodium hydroxide; dihydrogen peroxide; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; 1,2-dichloro-ethane;

DOI:10.1055/s-1993-25842

Reference yield:

cyclohex-1-enecarboxamide (22546-81-2) + triethyloxonium fluoroborate (368-39-8) → Cyclohex-1-enecarboximidic acid ethyl ester (1019020-13-3)

Guidance literature:

In 1,2-dichloro-ethane; for 18h; Ambient temperature;

DOI:10.1055/s-1993-25842

Reference yield:

Cyclohex-1-enecarboximidic acid ethyl ester (1019020-13-3) → (R)-4-Methoxymethyl-2-(1-methyl-2-phenyl-cyclohexyl)-4,5-dihydro-oxazole

Guidance literature:

Multi-step reaction with 2 steps

1: NH₃ / 1,2-dichloro-ethane / 18 h / Heating

2: 1.) THF, hexane, -40 deg C, 18 h 2.) rt, 18 h

With ammonia; In 1,2-dichloro-ethane;

DOI:10.1055/s-1993-25842

upstream raw materials:

cyclohex-1-enecarboxamide

triethyloxonium fluoroborate

cyclohex-1-enecarbonitrile

Downstream raw materials:

2-(1-cyclohexenyl)-4-methoxymethyl-2-oxazoline

2-vinyl-1-methyl-1-carboxaldehyde

2-phenyl-1-methyl-1-carboxaldehyde

(R)-4-Methoxymethyl-2-((1S,2S)-1-methyl-2-vinyl-cyclohexyl)-4,5-dihydro-oxazole

Refernces