N-4-bromobenzylidene-diphenylthiophosphinamide

Base Information

• Chemical Name: N-4-bromobenzylidene-diphenylthiophosphinamide
• CAS No.: 945492-02-4
• Molecular Formula: C₁₉H₁₅BrNPS
• Molecular Weight: 400.279
• Mol file: 945492-02-4.mol

Synonyms:

Chemical Property of N-4-bromobenzylidene-diphenylthiophosphinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-4-bromobenzylidene-diphenylthiophosphinamide

There total 1 articles about N-4-bromobenzylidene-diphenylthiophosphinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4-bromobenzaldehyde diethyl acetal (34421-94-8) + P,P-diphenylphosphinothioic amide (17366-80-2) → N-4-bromobenzylidene-diphenylthiophosphinamide (945492-02-4)

Guidance literature:

at 120 - 160 ℃;

DOI:10.1002/hc.20412

Reference yield: 90.0%

N-4-bromobenzylidene-diphenylthiophosphinamide (945492-02-4) + nitromethane (75-52-5) → C20H18BrN2O2PS (1201630-10-5)

Guidance literature:

With N,N,N',N'-tetramethylguanidine; at 20 ℃; for 0.166667h; Neat (no solvent);

DOI:10.1016/j.tetasy.2009.08.025

Reference yield:

N-4-bromobenzylidene-diphenylthiophosphinamide (945492-02-4) + 2-azido-1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)ethan-1-one → C28H24BrN6OPS + C28H24BrN6OPS

Guidance literature:

With (R)-(+)-(4,4'-bi-1,3-benzodioxole)-5,5'-diylbis(di(3,5-dimethylphenyl)phosphine); tetrakis(actonitrile)copper(I) hexafluorophosphate; N,N,N′,N′-tetramethyl-N″-tert-butylguanidine; In tetrahydrofuran; at -60 ℃; for 24h; Inert atmosphere; Glovebox;

DOI:10.1002/chem.201503921

upstream raw materials:

4-bromobenzaldehyde diethyl acetal

P,P-diphenylphosphinothioic amide

Downstream raw materials:

C₂₀H₁₈BrN₂O₂PS

Refernces