Technology Process of 3-methoxy-6-(3'-methoxybenzylthio)-2-(pyridin-4''-yl)imidazo<1,2-b>pyridazine
There total 5 articles about 3-methoxy-6-(3'-methoxybenzylthio)-2-(pyridin-4''-yl)imidazo<1,2-b>pyridazine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: bromine, HBr / acetic acid / 1.) 35-40 deg C, 1.5 h, 2.) 75 deg C,1 h
2: sodium hydrogen carbonate / ethanol / 4 h / 85 - 90 °C
3: diethyl ether / 20 °C
With
hydrogen bromide; bromine; sodium hydrogencarbonate;
In
diethyl ether; ethanol; acetic acid;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.16 g / sodium hydroxide / 16 h / 115 °C
2: sodium hydrogen carbonate / ethanol / 4 h / 85 - 90 °C
3: diethyl ether / 20 °C
With
sodium hydroxide; sodium hydrogencarbonate;
In
diethyl ether; ethanol;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydrogen carbonate / ethanol / 4 h / 85 - 90 °C
2: diethyl ether / 20 °C
With
sodium hydrogencarbonate;
In
diethyl ether; ethanol;
