C₂₅H₃₂N₁₂O₁₁

Base Information

• Chemical Name: C₂₅H₃₂N₁₂O₁₁
• CAS No.: 1147358-86-8
• Molecular Formula: C₂₅H₃₂N₁₂O₁₁
• Molecular Weight: 676.603
• Mol file: 1147358-86-8.mol

Synonyms:

Chemical Property of C₂₅H₃₂N₁₂O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₂N₁₂O₁₁

There total 3 articles about C₂₅H₃₂N₁₂O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

benzaldehyde dimethyl acetal (1125-88-8) + 1,3,6',3”-tetra-azido-kanamycin A (1037515-73-3) → 1,3,6',3''-tetraazido-5,2',4'',6''-di-O-benzylidenekanamycin A (1147358-84-6) + C25H32N12O11 (1147358-86-8)

Guidance literature:

With toluene-4-sulfonic acid; In N,N-dimethyl-formamide; at 68 ℃; for 12h;

DOI:10.1021/jo302247x

Reference yield:

Kanamycin A sulfate (3847-27-6,25389-94-0,64013-70-3,81129-79-5,84278-20-6,94108-19-7,94237-36-2,133-92-6) → 1,3,6',3''-tetraazido-5,2',4'',6''-di-O-benzylidenekanamycin A (1147358-84-6) + C25H32N12O11 (1147358-86-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide; trifluoromethylsulfonic anhydride; copper(II) sulfate; triethylamine / acetonitrile; water / 0 - 20 °C

2: toluene-4-sulfonic acid / N,N-dimethyl-formamide / 12 h / 68 °C

With sodium azide; trifluoromethylsulfonic anhydride; toluene-4-sulfonic acid; copper(II) sulfate; triethylamine; In water; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/jo302247x

Reference yield:

C32H42N12O18 → 1,3,6',3''-tetraazido-5,2',4'',6''-di-O-benzylidenekanamycin A (1147358-84-6) + C25H32N12O11 (1147358-86-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methylate; methanol / 4 h / 20 °C / pH 11

2: toluene-4-sulfonic acid / N,N-dimethyl-formamide / 12 h / 68 °C

With methanol; sodium methylate; toluene-4-sulfonic acid; In N,N-dimethyl-formamide;

DOI:10.1021/jo302247x

upstream raw materials:

Kanamycin A sulfate

benzaldehyde dimethyl acetal

1,3,6',3”-tetra-azido-kanamycin A

Refernces