2-bromopropyl benzyl(phenyl)carbamate

Base Information

• Chemical Name: 2-bromopropyl benzyl(phenyl)carbamate
• CAS No.: 1239921-40-4
• Molecular Formula: C₁₇H₁₈BrNO₂
• Molecular Weight: 348.239
• Mol file: 1239921-40-4.mol

Synonyms:

Chemical Property of 2-bromopropyl benzyl(phenyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-bromopropyl benzyl(phenyl)carbamate

There total 1 articles about 2-bromopropyl benzyl(phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromopropanol (598-18-5) + bis(trichloromethyl) carbonate (32315-10-9) + N-Benzylaniline (758640-21-0,103-32-2) → 2-bromopropyl benzyl(phenyl)carbamate (1239921-40-4)

Guidance literature:

2-bromopropanol; bis(trichloromethyl) carbonate; With 2,6-dimethylpyridine; In diethyl ether; at -78 - 20 ℃; Inert atmosphere;

N-Benzylaniline; With 2,6-dimethylpyridine; In diethyl ether; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/ja105924f

Reference yield:

2-bromopropyl benzyl(phenyl)carbamate (1239921-40-4) + C18H37BOSi (958882-35-4) → 7-((tert-butyldimethylsilyl)oxy)-2-methylheptyl benzyl(phenyl)carbamate

Guidance literature:

C₁₈H₃₇BOSi; With potassium tert-butylate; hexan-1-ol; In di-isopropyl ether; for 0.75h; Inert atmosphere;

2-bromopropyl benzyl(phenyl)carbamate; With diethylene glycol dimethyl ether; (S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine; In di-isopropyl ether; at 20 ℃; for 72h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ja105924f

Reference yield:

2-bromopropyl benzyl(phenyl)carbamate (1239921-40-4) + C18H37BOSi (958882-35-4) → 7-((tert-butyldimethylsilyl)oxy)-2-methylheptyl benzyl(phenyl)carbamate

Guidance literature:

C₁₈H₃₇BOSi; With potassium tert-butylate; hexan-1-ol; In di-isopropyl ether; for 0.75h; Inert atmosphere;

2-bromopropyl benzyl(phenyl)carbamate; With diethylene glycol dimethyl ether; (1R,2R)-(+)-N,N'-dimethyl-1,2-diphenyl-ethylenediamine; In di-isopropyl ether; at 20 ℃; for 72h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ja105924f

upstream raw materials:

2-bromopropanol

bis(trichloromethyl) carbonate

N-Benzylaniline

Downstream raw materials:

(S)-2-methyloctyl benzyl(phenyl)carbamate

(S)-2-methyl-5-phenylpentyl benzyl(phenyl)carbamate

(R)-2-methyl-5-phenylpentyl benzyl(phenyl)carbamate

Refernces