4-Trifluormethyl-3'-ethoxy-benzophenon

Base Information

• Chemical Name: 4-Trifluormethyl-3'-ethoxy-benzophenon
• CAS No.: 21084-28-6
• Molecular Formula: C₁₆H₁₃F₃O₂
• Molecular Weight: 294.273
• Mol file: 21084-28-6.mol

Synonyms:

Chemical Property of 4-Trifluormethyl-3'-ethoxy-benzophenon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Trifluormethyl-3'-ethoxy-benzophenon

There total 1 articles about 4-Trifluormethyl-3'-ethoxy-benzophenon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-trifluoromethylphenyl bromide (402-43-7) + 3-ethoxybenzaldehyde (22924-15-8) → 4-Trifluormethyl-3'-ethoxy-benzophenon (21084-28-6)

Guidance literature:

Multistep reaction; (i) Mg, Et₂O, (ii) /BRN= 2083854/, (iii) aq. Na₂Cr₂O₇, H₂SO₄, AcOH, benzene;

DOI:10.1021/jm00301a006

Reference yield:

4-Trifluormethyl-3'-ethoxy-benzophenon (21084-28-6) → 4'-trifluoromethyl-3-hydroxy-benzophenone (21084-29-7)

Guidance literature:

With Pyridine hydrobromide; at 210 ℃;

DOI:10.1021/jm00301a006

Reference yield:

4-Trifluormethyl-3'-ethoxy-benzophenon (21084-28-6) → 4-Trifluormethyl-3'-hydroxy-benzophenon-guanylhydrazon

Guidance literature:

Multi-step reaction with 2 steps

1: Py*HBr / 210 °C

2: aq. HCl / ethane-1,2-diol

With hydrogenchloride; Pyridine hydrobromide; In ethylene glycol;

DOI:10.1021/jm00301a006

upstream raw materials:

p-trifluoromethylphenyl bromide

3-ethoxybenzaldehyde

Downstream raw materials:

4'-trifluoromethyl-3-hydroxy-benzophenone