2-Amino-2-(2-fluorophenyl)acetic acid

Base Information Edit

Chemical Name:2-Amino-2-(2-fluorophenyl)acetic acid
CAS No.:84145-28-8
Molecular Formula:C8H8FNO2
Molecular Weight:169.155
Hs Code.:2922499990
European Community (EC) Number:282-253-9
Nikkaji Number:J1.289.630A
ChEMBL ID:CHEMBL383715
Mol file:84145-28-8.mol

Synonyms:84145-28-8;2-amino-2-(2-fluorophenyl)acetic acid;Amino(2-fluorophenyl)acetic acid;Amino-(2-fluoro-phenyl)-acetic acid;2-(2-FLUOROPHENYL)GLYCINE;2-fluoro-dl-phenylglycine;MFCD00042726;CHEMBL383715;DL-2-FLUOROPHENYLGLYCINE;( inverted exclamation markA)-amino(2-fluorophenyl)acetic acid;(S)-AMINO-(2-FLUORO-PHENYL)-ACETIC ACID;Bionet2_000821;2-(2-FLUOROPHENYL)-DL-GLYCINE;dl-O-Fluorophenylglycine;D0V6SS;dl-(2-Fluorophenyl)-glycine;SCHEMBL2628067;2-Fluoro-dl-alpha-phenylglycine;Amino-(2-Fluorophenyl)acetic acid;HMS1366F07;2-Fluoro-dl-.alpha.-phenylglycine;2-Fluoro-DL- alpha -phenylglycine;Amino(2-fluorophenyl)acetic acid #;BBL022165;BDBM50179723;STK130871;2-amino-2-(2-fluorophenyl)aceticacid;AKOS000174981;AKOS016045334;6L-340S;AB30501;AB32730;HY-W026894;(+-)-amino(2-fluorophenyl)acetic acid;2-Fluoro-DL-alpha-phenylglycine, 98%;SY265519;Benzeneacetic acid, alpha-amino-2-fluoro-;BB 0249645;CS-0070918;FT-0778176;EN300-70283;(+/-)-AMINO(2-FLUOROPHENYL)ACETIC ACID;(S)-AMINO-(2-FLUORO-PHENYL)-ACETICACID;A923267;F2167-0075;Z317024726

Suppliers and Price of 2-Amino-2-(2-fluorophenyl)acetic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2-Fluorophenyl)glycine
100mg
$ 45.00

TRC
(2-Fluorophenyl)glycine
500mg
$ 65.00

SynQuest Laboratories
(2-Fluorophenyl)glycine 97%
1 g
$ 45.00

SynQuest Laboratories
(2-Fluorophenyl)glycine 97%
5 g
$ 150.00

Sigma-Aldrich
2-Fluoro-DL-α-phenylglycine 98%
10g
$ 335.00

Matrix Scientific
(2-Fluorophenyl)glycine 98%
5g
$ 104.00

Matrix Scientific
(2-Fluorophenyl)glycine 98%
1g
$ 24.00

Crysdot
2-Amino-2-(2-fluorophenyl)aceticacid 97%
25g
$ 301.00

Chemenu
(2-Fluorophenyl)glycine 97%
25g
$ 284.00

Ambeed
2-Amino-2-(2-fluorophenyl)aceticacid 98%
250mg
$ 27.00

Total 31 raw suppliers

Chemical Property of 2-Amino-2-(2-fluorophenyl)acetic acid Edit

Chemical Property:

Melting Point:290oC (subl.)(lit.)
Boiling Point:283.1 °C at 760 mmHg
PKA:1.66±0.10(Predicted)
Flash Point:125 °C
PSA：63.32000
Density:1.347 g/cm³
LogP:1.61040
Storage Temp.:2-8°C(protect from light)
Solubility.:Aqueous acid (Slightly, Heated, Sonicated)
XLogP3:-1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:169.05390666
Heavy Atom Count:12
Complexity:174

Purity/Quality:

99% ^*data from raw suppliers

(2-Fluorophenyl)glycine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(C(=O)O)N)F
Uses (2-Fluorophenyl)glycine

Technology Process of 2-Amino-2-(2-fluorophenyl)acetic acid

There total 11 articles about 2-Amino-2-(2-fluorophenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 79477-86-4
2-fluorophenylglyoxylic acid

: 84145-28-8,138751-03-8,2343-27-3
(+/-)-2-amino-2'-fluorophenylacetic acid

Guidance literature:: With (S)-2-amino-(2-chlorophenyl)ethanoic acid; In water; acetonitrile; at 50 ℃; for 36h; Reflux; Inert atmosphere;
DOI:10.1021/acs.joc.0c01302

Reference yield: 78.0%

: 271583-21-2
benzylamino-(2-fluoro-phenyl)-acetic acid

: 84145-28-8,138751-03-8,2343-27-3
(+/-)-2-amino-2'-fluorophenylacetic acid

Guidance literature:: With sodium hydroxide; hydrazine hydrate; palladium on activated charcoal; In water; for 10h; Heating;
DOI:10.1080/00397910008087127