L-O-(benzyl)serineethyl ester

Base Information

• Chemical Name: L-O-(benzyl)serineethyl ester
• CAS No.: 78746-55-1
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.272
• Mol file: 78746-55-1.mol

Synonyms:

Chemical Property of L-O-(benzyl)serineethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of L-O-(benzyl)serineethyl ester

There total 2 articles about L-O-(benzyl)serineethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-benzylserine (5445-44-3,32520-12-0) → O-benzyl-DL-serine ethyl ester (78746-55-1)

Guidance literature:

With hydrogenchloride;

DOI:10.1246/bcsj.30.976

Reference yield:

→ L-O-(benzyl)serineethyl ester (78746-55-1)

Guidance literature:

Reference yield:

L-O-(benzyl)serineethyl ester (78746-55-1) → (S)-3-Benzyloxy-2-(1-ethoxycarbonylmethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-ylamino)-propionic acid ethyl ester

Guidance literature:

Multi-step reaction with 2 steps

1: di-n-butyltin dichloride / CHCl₃ / 16 h / Heating

2: acetic acid, NaBH₃CN / methanol / 16 h / Ambient temperature

With dibutyltin chloride; sodium cyanoborohydride; acetic acid; In methanol; chloroform;

DOI:10.1021/jm00149a010

upstream raw materials:

O-benzylserine

Downstream raw materials:

O-benzyl-N-(N-benzyloxycarbonyl-glycyl)-DL-serine ethyl ester

N-Ethoxymalonyl-O-benzyl-D,L-serinethylester

O-benzyl-N-(N-benzyloxycarbonyl-glycyl)-serine hydrazide

Refernces