Technology Process of 2-<2,3,5,10-Tetrahydro-1,1,3,3-tetramethyl-10-oxo-1H-cyclopentacridin-5-yl>benzoesaeure-methylester
There total 8 articles about 2-<2,3,5,10-Tetrahydro-1,1,3,3-tetramethyl-10-oxo-1H-cyclopentacridin-5-yl>benzoesaeure-methylester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
PPA;
at 130 - 140 ℃;
for 4h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 47 percent / NaNO2, conc. HNO3 / acetic acid / 0.25 h / 10 - 20 °C
2: 88 percent / sat. aq. NH3, NH4Cl / 20 h / 140 - 150 °C / 18751.5 Torr
3: 24 percent / K2CO3 / Naturkupfer C
4: 58 percent / H2 / Raney-nickel / ethyl acetate / 24 h
5: NaNO2, conc. HCl / H2O / 0 °C
6: 45percent hypophosphoric acid / 1) refrigerator, 8 h, 2) room temp., 8 h
7: 55 percent / PPA / 4 h / 130 - 140 °C
With
hydrogenchloride; ammonium hydroxide; hydrogen; nitric acid; potassium carbonate; ammonium chloride; hypophosphoric acid; sodium nitrite;
Naturkupfer C; nickel;
In
water; acetic acid; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 24 percent / K2CO3 / Naturkupfer C
2: 58 percent / H2 / Raney-nickel / ethyl acetate / 24 h
3: NaNO2, conc. HCl / H2O / 0 °C
4: 45percent hypophosphoric acid / 1) refrigerator, 8 h, 2) room temp., 8 h
5: 55 percent / PPA / 4 h / 130 - 140 °C
With
hydrogenchloride; hydrogen; potassium carbonate; hypophosphoric acid; sodium nitrite;
Naturkupfer C; nickel;
In
water; ethyl acetate;
