3α,20α-dibenzoyloxy-5β-pregnane

Base Information

• Chemical Name: 3α,20α-dibenzoyloxy-5β-pregnane
• CAS No.: 14895-24-0
• Molecular Formula: C₃₅H₄₄O₄
• Molecular Weight: 528.732
• Mol file: 14895-24-0.mol

Synonyms:

Chemical Property of 3α,20α-dibenzoyloxy-5β-pregnane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3α,20α-dibenzoyloxy-5β-pregnane

There total 4 articles about 3α,20α-dibenzoyloxy-5β-pregnane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

pregnanediol (80-92-2) + benzoyl chloride (98-88-4) → 3α,20α-dibenzoyloxy-5β-pregnane (14895-24-0,25390-11-8)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 6h;

DOI:10.1021/jacs.8b05753

Reference yield:

3β-hydroxy-5β-pregnan-20-one (128-21-2) → 3β,20αF-bis-benzoyloxy-5β-pregnane (14895-24-0,25390-11-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium

2: pyridine

With pyridine; sodium;

Reference yield:

UC1020 (80-90-0) + benzoyl chloride (98-88-4) → 3β,20αF-bis-benzoyloxy-5β-pregnane (14895-24-0,25390-11-8)

Guidance literature:

With pyridine;

upstream raw materials:

pregnanediol

benzoyl chloride

UC₁₀₂₀

3β-hydroxy-5β-pregnan-20-one

Refernces