N^ω-benzyloxycarbonyl-N^α-(N^α,N^δ,N^ω-tris-benzyloxycarbonyl-L-arginyl)-L-arginine benzyl ester

Base Information

• Chemical Name: N^ω-benzyloxycarbonyl-N^α-(N^α,N^δ,N^ω-tris-benzyloxycarbonyl-L-arginyl)-L-arginine benzyl ester
• CAS No.: 79220-33-0
• Molecular Formula: C₅₁H₅₆N₈O₁₁
• Molecular Weight: 957.053
• Mol file: 79220-33-0.mol

Synonyms:

Chemical Property of N^ω-benzyloxycarbonyl-N^α-(N^α,N^δ,N^ω-tris-benzyloxycarbonyl-L-arginyl)-L-arginine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^ω-benzyloxycarbonyl-N^α-(N^α,N^δ,N^ω-tris-benzyloxycarbonyl-L-arginyl)-L-arginine benzyl ester

There total 3 articles about N^ω-benzyloxycarbonyl-N^α-(N^α,N^δ,N^ω-tris-benzyloxycarbonyl-L-arginyl)-L-arginine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nα,Nδ,Nω-tris(benzyloxycarbonyl)-L-arginine (14611-34-8) + Arg-OBzl (113184-78-4) → Nω-benzyloxycarbonyl-Nα-(Nα,Nδ,Nω-tris-benzyloxycarbonyl-L-arginyl)-L-arginine benzyl ester (79220-33-0)

Guidance literature:

With dicyclohexyl-carbodiimide;

DOI:10.4039/Ent133439-4

Reference yield:

Nα,Nγ-bis(benzyloxycarbonyl)-L-arginine (53934-75-1) → Nω-benzyloxycarbonyl-Nα-(Nα,Nδ,Nω-tris-benzyloxycarbonyl-L-arginyl)-L-arginine benzyl ester (79220-33-0)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / Behandeln des erhaltenen Reaktionsprodukts mit HCl enthaltendem Benzylalkohol

2: chlorocarbonic acid isobutyl ester

With thionyl chloride; isobutyl chloroformate;

DOI:10.1021/jo01362a052

Reference yield:

L-arginine (74-79-3,25212-18-4) → Nω-benzyloxycarbonyl-Nα-(Nα,Nδ,Nω-tris-benzyloxycarbonyl-L-arginyl)-L-arginine benzyl ester (79220-33-0)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorocarbonic acid benzyl ester; aqueous NaOH / Reinigung ueber das Natrium-Salz

2: chlorocarbonic acid isobutyl ester

With sodium hydroxide; benzyl chloroformate; isobutyl chloroformate;

DOI:10.1021/jo01362a052

upstream raw materials:

N^α,N^δ,N^ω-tris(benzyloxycarbonyl)-L-arginine

Arg-OBzl

L-arginine

N^α,N^γ-bis(benzyloxycarbonyl)-L-arginine