4-hydroxy-3,5-di-tert-butylbenzoxy acetic acid

Base Information

• Chemical Name: 4-hydroxy-3,5-di-tert-butylbenzoxy acetic acid
• CAS No.: 127900-99-6
• Molecular Formula: C₁₇H₂₆O₄
• Molecular Weight: 294.391
• Mol file: 127900-99-6.mol

Synonyms:

Chemical Property of 4-hydroxy-3,5-di-tert-butylbenzoxy acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-hydroxy-3,5-di-tert-butylbenzoxy acetic acid

There total 3 articles about 4-hydroxy-3,5-di-tert-butylbenzoxy acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

glycolic Acid (79-14-1) + 3,5-di-tert-butyl-4-hydroxybenzyl acetate (14387-17-8) → 4-hydroxy-3,5-di-tert-butylbenzoxy acetic acid (127900-99-6) + glycolic acid 4-hydroxy-3,5-di-tert-butylbenzyl ester (127901-00-2)

Guidance literature:

With perchloric acid; Heating;

DOI:10.1007/BF00962439

Reference yield:

tris-(3,5-di-tert-butyl-4-hydroxybenzyl)-amine (752-60-3) → 4-hydroxy-3,5-di-tert-butylbenzoxy acetic acid (127900-99-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / H₂O / acetone / 1) 1h, reflux, 2) after addition of water 1h, reflux

2: 75 percent / HClO₄ / Heating

With perchloric acid; water; In acetone;

DOI:10.1007/BF00962439

Reference yield:

N,N-dimethyl-(3,5-di-tert-butyl-4-hydroxybenzyl)amine (88-27-7) → 4-hydroxy-3,5-di-tert-butylbenzoxy acetic acid (127900-99-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / acetone / Heating

2: 75 percent / HClO₄ / Heating

With perchloric acid; In acetone;

DOI:10.1007/BF00962439

upstream raw materials:

glycolic Acid

3,5-di-tert-butyl-4-hydroxybenzyl acetate

tris-(3,5-di-tert-butyl-4-hydroxybenzyl)-amine

N,N-dimethyl-(3,5-di-tert-butyl-4-hydroxybenzyl)amine

Refernces