C₃₀H₃₅FN₄O₂

Base Information

• Chemical Name: C₃₀H₃₅FN₄O₂
• CAS No.: 1352428-58-0
• Molecular Formula: C₃₀H₃₅FN₄O₂
• Molecular Weight: 502.632
• Mol file: 1352428-58-0.mol

Synonyms:

Chemical Property of C₃₀H₃₅FN₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₃₅FN₄O₂

There total 12 articles about C₃₀H₃₅FN₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(bromo-methoxycarbonyl-methyl)-piperidine-1-carboxylic acid tert-butyl ester (881016-88-2) → C30H35FN4O2 (1352428-58-0)

Guidance literature:

Multi-step reaction with 6 steps

1: sodium azide / N,N-dimethyl-formamide

2: 5%-palladium/activated carbon; hydrogen

3: ammonia / methanol

4: sodium tris(acetoxy)borohydride / dichloromethane

5: hydrogenchloride / methanol

6: triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate

With hydrogenchloride; sodium azide; 5%-palladium/activated carbon; ammonia; hydrogen; sodium tris(acetoxy)borohydride; triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.09.113

Reference yield:

indole (120-72-9) → C30H35FN4O2 (1352428-58-0)

Guidance literature:

Multi-step reaction with 6 steps

1: potassium hydroxide / methanol / Heating

2: palladium 10% on activated carbon; hydrogen

3: hydrogenchloride / water; acetonitrile

4: sodium tris(acetoxy)borohydride / dichloromethane

5: hydrogenchloride / methanol

6: triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; sodium tris(acetoxy)borohydride; triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; potassium hydroxide; In methanol; dichloromethane; water; acetonitrile;

DOI:10.1016/j.bmcl.2011.09.113

Reference yield:

cyclohexanedione monoethylene ketal (4746-97-8) → C30H35FN4O2 (1352428-58-0)

Guidance literature:

Multi-step reaction with 6 steps

1: potassium hydroxide / methanol / Heating

2: palladium 10% on activated carbon; hydrogen

3: hydrogenchloride / water; acetonitrile

4: sodium tris(acetoxy)borohydride / dichloromethane

5: hydrogenchloride / methanol

6: triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; sodium tris(acetoxy)borohydride; triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; potassium hydroxide; In methanol; dichloromethane; water; acetonitrile;

DOI:10.1016/j.bmcl.2011.09.113

upstream raw materials:

indole

4-(bromo-methoxycarbonyl-methyl)-piperidine-1-carboxylic acid tert-butyl ester

cyclohexanedione monoethylene ketal

tert-butyl 4-(1-azido-2-methoxy-2-oxoethyl)piperidine-1-carboxylate

Refernces