Technology Process of C28H40NO7PSi
There total 5 articles about C28H40NO7PSi which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyl (4R)-2-oxo-4-(triisopropylsilyloxy)piperidine-1-carboxylate;
With
potassium hexamethylsilazane;
In
tetrahydrofuran;
at -78 ℃;
for 1.5h;
chlorophosphoric acid diphenyl ester;
In
tetrahydrofuran;
at -78 ℃;
for 1h;
DOI:10.1055/s-0032-1317490
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / 8 h / 40 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 0 °C / Inert atmosphere
3.1: potassium hexamethylsilazane / tetrahydrofuran / 1.5 h / -78 °C
3.2: 1 h / -78 °C
With
1H-imidazole; n-butyllithium; potassium hexamethylsilazane;
In
tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1055/s-0032-1317490
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / 8 h / 40 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 0 °C / Inert atmosphere
3.1: potassium hexamethylsilazane / tetrahydrofuran / 1.5 h / -78 °C
3.2: 1 h / -78 °C
With
1H-imidazole; n-butyllithium; potassium hexamethylsilazane;
In
tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1055/s-0032-1317490
