Benzothiazolium, 2-methyl-3-(2-oxo-2-phenylethyl)-, bromide

Base Information

• Chemical Name: Benzothiazolium, 2-methyl-3-(2-oxo-2-phenylethyl)-, bromide
• CAS No.: 1088-44-4
• Molecular Formula: C16H14NOS.Br
• Molecular Weight: 348.263
• Mol file: 1088-44-4.mol

Synonyms:

Chemical Property of Benzothiazolium, 2-methyl-3-(2-oxo-2-phenylethyl)-, bromide

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzothiazolium, 2-methyl-3-(2-oxo-2-phenylethyl)-, bromide

There total 1 articles about Benzothiazolium, 2-methyl-3-(2-oxo-2-phenylethyl)-, bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-Methylbenzothiazole (120-75-2) + α-bromoacetophenone (70-11-1) → 3-phenacyl-2-methylbenzothiazolium bromide (1088-44-4)

Guidance literature:

at 100 - 120 ℃; for 6h;

Reference yield: 100.0%

3-phenacyl-2-methylbenzothiazolium bromide (1088-44-4) → 2-{2-Methyl-2-[3-(2-oxo-2-phenyl-ethyl)-3H-benzothiazol-(2E)-ylidenemethyl]-benzothiazol-3-yl}-1-phenyl-ethanone (80108-11-8)

Guidance literature:

With triethylamine; In acetonitrile; at 0 ℃; for 0.5h;

Reference yield: 84.0%

3-phenacyl-2-methylbenzothiazolium bromide (1088-44-4) + 3-(2,3-diphenyl-2-cyclopropenylidene)pentane-2,4-dione → 3-(1-acetylacetonyl)-9-phenacyl-2,3a-diphenyl-3a,9-dihydrocyclopenta<1,4>benzothiazine (83996-35-4) + 2-(1-acetylacetonyl)-9-phenacyl-1,3-diphenyl-3a,9-dihydrocyclopenta<1,4>benzothiazine (83996-37-6) + C36H29NO3S (83996-32-1)

Guidance literature:

With triethylamine; for 0.5h; Ambient temperature;

DOI:10.1246/cl.1982.1353

upstream raw materials:

2-Methylbenzothiazole

α-bromoacetophenone

Downstream raw materials:

1-phenyl-2-[2-(2,4,6-trinitro-benzylidene)-benzothiazol-3-yl]-ethanone

2-phenylpyrrolo<2,1-b>benzothiazole

2-(2-Phenyl-benzo[d]pyrrolo[2,1-b]thiazol-3-yl)-succinonitrile

2-{2-Methyl-2-[3-(2-oxo-2-phenyl-ethyl)-3H-benzothiazol-(2E)-ylidenemethyl]-benzothiazol-3-yl}-1-phenyl-ethanone

Refernces

• 1、 Briks, Yu. L.,Romanov, N. N.. "PYRROLOBENZOTHIAZOLE DERIVATIVES". . p. 438 - 442. Retrieved 2007/10/02.