(R)-3-methyl-N¹,N⁶-diphenylhexanediamide

Base Information

• Chemical Name: (R)-3-methyl-N¹,N⁶-diphenylhexanediamide
• CAS No.: 1402081-42-8
• Molecular Formula: C₁₉H₂₂N₂O₂
• Molecular Weight: 310.396
• Mol file: 1402081-42-8.mol

Synonyms:

Chemical Property of (R)-3-methyl-N¹,N⁶-diphenylhexanediamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-3-methyl-N¹,N⁶-diphenylhexanediamide

There total 2 articles about (R)-3-methyl-N¹,N⁶-diphenylhexanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H28O8 + aniline (62-53-3) → (R)-3-methyl-N1,N6-diphenylhexanediamide (1402081-42-8) + (S)-3-methyl-N1,N6-diphenylhexanediamide

Guidance literature:

In tetrahydrofuran; at 35 ℃; for 8h;

DOI:10.1021/ja309262f DOI:10.1021/ja309262f

Reference yield:

(R)-3-methylhexanedioic acid (623-82-5) + aniline (62-53-3) → (R)-3-methyl-N1,N6-diphenylhexanediamide (1402081-42-8)

Guidance literature:

(R)-3-methylhexanedioic acid; With triethylamine; isobutyl chloroformate; In tetrahydrofuran; at 0 ℃; for 0.25h;

aniline; In tetrahydrofuran; at 35 ℃; for 8h;

DOI:10.1021/ja3112719

upstream raw materials:

aniline

(R)-3-methylhexanedioic acid

Refernces

• 1、 Zhou, Lin,Liu, Xiaohua,Ji, Jie,Zhang, Yuheng,Hu, Xiaolei,Lin, Lili,Feng, Xiaoming. "Enantioselective baeyer-villiger oxidation: Desymmetrization of meso cyclic ketones and kinetic resolution of racemic 2-arylcyclohexanones". supporting information. p. 17023 - 17026. Retrieved 2013/01/15.