N-(p-Decyloxy-benzyloxy-carbonyl)-Ala-p-dodecylbenzylester

Base Information

• Chemical Name: N-(p-Decyloxy-benzyloxy-carbonyl)-Ala-p-dodecylbenzylester
• CAS No.: 5519-21-1
• Molecular Formula: C₄₀H₆₃NO₅
• Molecular Weight: 637.944
• Mol file: 5519-21-1.mol

Synonyms:

Chemical Property of N-(p-Decyloxy-benzyloxy-carbonyl)-Ala-p-dodecylbenzylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(p-Decyloxy-benzyloxy-carbonyl)-Ala-p-dodecylbenzylester

There total 3 articles about N-(p-Decyloxy-benzyloxy-carbonyl)-Ala-p-dodecylbenzylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-dodecylbenzene (123-01-3) → N-(p-Decyloxy-benzyloxy-carbonyl)-Ala-p-dodecylbenzylester (5519-21-1)

Guidance literature:

Multi-step reaction with 3 steps

1: PCl₃, H₂SO₄ / methanol

2: KOAc / acetic acid / 140 - 150 °C

3: Me₂NCH(OCH₂tBu)2 / CH₂Cl₂

With sulfuric acid; potassium acetate; N,N-dimethylformamide dineopentyl acetal; phosphorus trichloride; In methanol; dichloromethane; acetic acid;

DOI:10.1002/hlca.19650480734

Reference yield:

4-dodecylbenzyl chloride (104-37-0) → N-(p-Decyloxy-benzyloxy-carbonyl)-Ala-p-dodecylbenzylester (5519-21-1)

Guidance literature:

Multi-step reaction with 2 steps

1: KOAc / acetic acid / 140 - 150 °C

2: Me₂NCH(OCH₂tBu)2 / CH₂Cl₂

With potassium acetate; N,N-dimethylformamide dineopentyl acetal; In dichloromethane; acetic acid;

DOI:10.1002/hlca.19650480734

Reference yield:

p-(n-dodecyl)benzyl alcohol (5519-35-7) + (S)-2-(4-Decyloxy-benzyloxycarbonylamino)-propionic acid → N-(p-Decyloxy-benzyloxy-carbonyl)-Ala-p-dodecylbenzylester (5519-21-1)

Guidance literature:

With N,N-dimethylformamide dineopentyl acetal; In dichloromethane;

DOI:10.1002/hlca.19650480734

upstream raw materials:

p-(n-dodecyl)benzyl alcohol

1-dodecylbenzene

4-dodecylbenzyl chloride