Technology Process of C22H20Cl2F3N5O3
There total 13 articles about C22H20Cl2F3N5O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 4 steps
1: N-chloro-succinimide / N,N-dimethyl-formamide / 0.67 h / 100 °C
2: thionyl chloride / 3 h / Reflux
3: tetrahydrofuran / 20 °C / Cooling with ice
4: triethylamine / tetrahydrofuran / 8 h / 20 °C
With
N-chloro-succinimide; thionyl chloride; triethylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/cjoc.201200362
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: hydrazine hydrate / ethanol / 36 h / Reflux
2.1: sodium; ethanol / 0.17 h / Reflux
2.2: Reflux
3.1: dipotassium peroxodisulfate; sulfuric acid / acetonitrile / 4.5 h / Reflux
4.1: potassium carbonate / N,N-dimethyl-formamide / 100 °C
5.1: sodium hydroxide / water; methanol / 6 h / 20 °C
6.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 4 h / 20 °C
7.1: triethylamine / tetrahydrofuran / 8 h / 20 °C
With
dipotassium peroxodisulfate; oxalyl dichloride; ethanol; sulfuric acid; sodium; potassium carbonate; hydrazine hydrate; triethylamine; N,N-dimethyl-formamide; sodium hydroxide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1002/cjoc.201200362